Sperm Quality

Source: www.moreover.com --- 42 days ago
BARCELONA, Spain - Researchers in Scotland have found yet another reason for men to avoid becoming overweight. Besides the usual bogeymen such as heart disease, high blood pressure and the like, add lower Quality Sperm. In research presented Wednesday at ...

Source: www.ncbi.nlm.nih.gov --- 30 days ago
Related Articles Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human Sperm motility and acrosome reaction and as predictors of poor spermatozoan Quality. J Biol Chem. 2008 May 23;283(21):14479-89 Authors: Almog T, Lazar S, Reiss N, Etkovitz N, Milch E, Rahamim N, Dobkin-Bekman M, Rotem R, Kalina M, Ramon J, Raziel A, Brietbart H, Seger R, Naor Z Mature spermatozoa acquire progressive motility only after ejaculation. Their journey in the female reproductive tract also includes suppression of progressive motility, reactivation, capacitation, and hyperactivation of motility (whiplash), the mechanisms of which are obscure. MAPKs are key regulatory enzymes in cell signaling, participating in diverse cellular functions such as growth, differentiation, stress, and apoptosis. Here we report that ERK1/2 and p38 MAPK are primarily localized to the tail of mature human spermatozoa. Surprisingly, c-Jun N-terminal kinase 1/2, which is thought to be ubiquitously expressed, could not be detected in mature human spermatozoa. ERK1/2 stimulation is downstream to protein kinase C (PKC) activation, which is also present in the human Sperm tail (PKCbetaI and PKCepsilon). ERK1/2 stimulates and p38 inhibits forward and hyperactivated motility, respectively. Both ERK1/2 and p38 MAPK are involved in the acrosome reaction. Using a proteomic approach, we identified ARHGAP6, a RhoGAP, as an ERK substrate in PMA-stimulat ...

Source: www.theglobeandmail.com --- 42 days ago
Because fat tissue influences the metabolism of sex hormones, scientists think it might also disrupt Sperm production ...

Source: www.ctv.ca --- 42 days ago
Researchers in Scotland have found yet another reason for men to avoid becoming overweight. Besides the usual bogeymen such as heart disease, high blood pressure and the like, add lower Quality Sperm. ...

Source: www.medicalnewstoday.com --- 39 days ago
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology. Dr. Con Mallidis from Queen's University, Belfast, UK, said that, despite the prevailing view that it had little effect on male reproductive function, the Belfast group had shown that diabetes caused DNA damage in Sperm. ...

Source: www.eurekalert.org --- 42 days ago
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology on Wednesday 9 July. Dr. Con Mallidis from Queen's University, Belfast, UK, said that, despite the prevailing view that it had little effect on male reproductive function, the Belfast group had shown that diabetes caused DNA damage in Sperm. ...

Source: medical.bizcommunity.com --- 41 days ago
Being too fat can damage Sperm. Read full story... | Send to a friend ...

Source: www.thaindian.com --- 42 days ago
London, July 9 (IANS) Researchers from Queen’s University have shown that excess sugar in the blood directly affects Sperm Quality and consequently male fertility, overturning popular perceptions. The increasing number of youths being diagnosed with diabetes has coincided with global concerns over male fertility, pointed out Con Mallidis of Queen’s in Belfast, who led the [...] ...

Source: www.chattershmatter.com --- 27 days ago
Eating a lot of foods containing soy may be bad for a man’s Sperm count, meaning his level of fertility is low. This news is published in the journal Human Reproduction, and says that the more soy foods men eat, the less semen they produce and the poorer their Sperm is. The study featured 99 men, whose [...] ...

Source: www.wddty.com --- 13 days ago
Soy food and isoflavones, a hormone derived from soy products, can make men infertile, a new study has discovered. ...

Source: www.topix.com --- 42 days ago
Diabetes in men has a direct effect on fertility, a scientist told the 24th annual conference of the European Society of Human Reproduction and Embryology today . ...

Source: bestinternationalnews.com --- 42 days ago
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Source: www.ep89.com --- 30 days ago
bese men have poorer Quality Sperm, perhaps because too much fat around their testicles causes them to heat up, scientists have suggested. University of Aberdeen researchers looked at the Sperm of over 2,000 men in couples having problems conceiving. The heaviest men had a higher proportion of abnormal Sperm, as well as other problems. The scientists told a [...] ...

Source: abcnews.go.com --- 42 days ago
Researchers say obese men have lower-Quality Sperm than their slim counterparts. ...

Source: abclocal.go.com --- 26 days ago
Eating a half serving a day of soy based foods could be enough to significantly lower a man's Sperm count, according to the largest study in humans to look at the relationship between Sperm Quality and soy rich foods. ...

Source: news.bbc.co.uk --- 42 days ago
Obese men have poorer Quality Sperm, perhaps because too much fat around their testicles causes them to heat up, scientists have suggested. ...

Source: www.ncbi.nlm.nih.gov --- 15 days ago
Related Articles The relation between urinary metabolite of pyrethroid insecticides and semen Quality in humans. Fertil Steril. 2008 Jun;89(6):1743-50 Authors: Xia Y, Han Y, Wu B, Wang S, Gu A, Lu N, Bo J, Song L, Jin N, Wang X OBJECTIVE: To explore the possible association between internal exposure levels of 3-phenoxybenzoic acid (3-PBA), an urinary metabolite of pyrethroids, and altered semen Quality in Chinese men. DESIGN: A retrospective case-control study. SETTING: Center of clinical reproductive medicine. PATIENT(S): Three hundred seventy-six men with nonobstructive infertility. MAIN OUTCOME MEASURE(S): Urinary 3-PBA concentration, semen volume, Sperm concentration, Sperm number per ejaculum, Sperm motility, Sperm progression, and motion parameters. RESULT(S): The median 3-PBA concentration was 0.879 microg/g of creatinine. There was suggestive association between increased creatinine-adjusted 3-PBA quartiles and Sperm concentration (odd ratios for the first, second, third, and fourth quartiles were 1.00, 1.31, 1.73, and 2.04, respectively), whereas Sperm volume, Sperm number per ejaculum, and Sperm motility were weakly or nonsignificantly associated with 3-PBA quartiles. The Sperm progression and motion parameters associated with creatinine-adjusted 3-PBA levels were straight line velocity (VSL) and curvilinear velocity (VCL). CONCLUSION(S): These observed associations between 3-PBA levels and some altered semen Quality indicate ...

Source: www.ncbi.nlm.nih.gov --- 16 days ago
Related Articles PRENATAL TESTOSTERONE EXCESS REDUCES Sperm COUNT AND MOTILITY. Endocrinology. 2008 Jul 31; Authors: Recabarren SE, Rojas-García PP, Recabarren MP, Alfaro VH, Smith R, Padmanabhan V, Sir-Petermann T The reproductive system is extremely susceptible to insults from exposure to exogenous steroids during development. Excess prenatal testosterone exposure programs neuroendocrine, ovarian, and metabolic deficits in the female, features seen in women with polycystic ovary disease. The objective of this study was to determine if prenatal testosterone excess also disrupts the male reproductive system, using sheep as a model system. The extent of reproductive disruption was tested by assessing Sperm quantity and Quality as well as Leydig cell responsiveness to hCG. Males born to mothers treated with 30 mg testosterone propionate twice weekly from days 30 to 90 and with 40 mg testosterone propionate from day 90 to 120 of pregnancy (T-males) showed a significant reduction (P<0.05) in body weight, scrotal circumference and Sperm count compared to control males. Mean straight line velocity of sperms was also lower in T-males (P<0.05). Circulating testosterone levels in response to the hCG did not differ between groups. These findings demonstrate that exposure to excess testosterone during fetal development has a negative impact on reproductive health of the male offspring raising concerns relative to unintended human exposure to ster ...

Source: www.ncbi.nlm.nih.gov --- 9 days ago
Related Articles [Sperm morphology does not influence fertilization rate in vitro] Zhonghua Nan Ke Xue. 2008 Jul;14(7):610-3 Authors: Wu Y, Xu HM, Zhang SY, Xu WH, Tang F, Yang LH OBJECTIVE: To determine the correlation of the rate of morphologically normal Sperm, Sperm head defect, teratozoosperm index (TZI) and Sperm deformity index (SDI) with the fertilization outcome of IVF and intracytoplasmic Sperm injection (ICSI). METHODS: We detected normal Sperm morphology, Sperm head defect, TZI and SDI by Krüger's strict criteria and compared them with the rate of fertilization. RESULTS: In either IVF or ICSI, the fertilization rate did not show any correlation with the normal Sperm morphology rate, the head defect rate, TZI and SDI, nor any statistic differences were found in the rates of fertilization, clinical pregnancy and Quality embryos either between the SDI > 1.6 and the SDI < 1.6 groups (P > 0.05) or between the normal Sperm morphology rate > 15% and < 15% groups (P > 0.05). CONCLUSION: Sperm morphology has no predictive value for the rate of fertilization in vitro. PMID: 18686381 [PubMed - in process] ...