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Source: heartdisease.about.com --- 12 days ago
High HDL cholesterol levels were found in people that lived to be 100 years old ... Source: www.moreover.com --- 3 days ago
Site Map| News | SpaceFlight | Science | Technology | Entertainment | SpaceViews | NightSky | Ad Astra | SETI ... Source: www.moreover.com --- 2 hours ago
President Bush plans to sign a bill next week that commits the United States to spending about $40 billion over the next five years to fight AIDS overseas, a major expansion of what many consider his most successful foreign policy initiative. ... Source: www.ncbi.nlm.nih.gov --- 1 day ago
Related Articles How does suppression of IGF-1 signaling by DNA damage affect aging and Longevity? Mech Ageing Dev. 2008 May;129(5):243-53 Authors: Hinkal G, Donehower LA Long-lived animals have evolved a robust set of defenses to maintain genomic integrity over their entire lifespan. The DNA damage response and DNA repair pathways are critical pillars of organismal defenses, minimizing somatic mutations in both post-mitotic and mitotic cells. These genomic maintenance systems not only prevent the premature emergence of cancers but may also maintain normal tissue function and organismal Longevity. Genetic defects in a number of DNA repair and DNA damage response genes often leads to a dramatic increase in cancer incidence; in other cases, premature aging or progeroid syndromes may be induced. In this review, we discuss two recent reports of two nucleotide excision repair-deficient models that exhibit dramatic premature aging and shortened Longevity. The DNA repair defects were also associated with a significant inhibition of the growth hormone/insulin-like growth factor 1 (GH/IGF-1) axis, an endocrine signaling pathway shown to influence aging and Longevity in both vertebrates and invertebrates. Potential mechanisms of how DNA damage might affect IGF-1 signaling and aging are discussed, with a particular emphasis on the role of such signaling alterations in the adult tissue stem cell compartments. PMID: 18374391 [PubMed - indexed for ... Source: www.washingtonpost.com --- 3 hours ago
President Bush plans to sign a bill next week that commits the United States to spending about $40 billion over the next five years to fight AIDS overseas, a major expansion of what many consider his most successful foreign policy initiative. ... Source: uk.reuters.com --- 4 days ago
LONDON (Reuters) - The Pensions Regulator has delayed proposals to make pension schemes use more conservative mortality assumptions, after the move came under fire from industry groups which said it created unnecessary pressure. ... Source: blog.wired.com --- 12 hours ago
Two new studies have found the molecular link between circadian rhythm and metabolism -- and it turns out to be a protein targeted by resveratrol, a potentially Longevity-enhancing drug. Neither of the studies, published yesterday in Cell, tested the metabolic effects of resveratrol, but they strike a note of caution for those -- including myself -- who expect resveratrol to be the first of an entire class of drugs that slow the physical and mental deterioration of aging. Resveratrol's target is SIRT1, one of a group of proteins called sirtuins that maintain cellular function. But the researchers -- one group from the University of California, Irvine and another from the University of Geneva -- say that SIRT1 is also an important piece of our biological clocks: it links cell-level ciradian rhythms with body-level physiology, keeping appetite and wakefulness in a smoothly-regulated cycle. Whether sirtuin-activating drugs will interfere with this is unknown, but it shouldn't be hard to test. (Talk about a side effect: you'll live long and healthily, but have trouble sleeping and get hungry at inconvenient times! I'd take it.) In the meantime, though, the studies are an useful reminder that these drugs -- though extremely promising -- aren't yet proven. The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control [Cell] SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetyla ... Source: reddit.com --- 1 day ago
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Source: www.prweb.com --- 22 hours ago
News 12 Long Island extends contract with sports legend andlongest-running sports broadcaster in history. (PRWeb Jul 24, 2008) Read the full story at http://www.prweb.com/releases/2008/07/prweb1143214.htm ... Source: www.medicinenet.com --- 1 hour ago
Title: Studies Link Circadian Rhythm, Metabolism, Longevity to One Protein Category: Health News Created: 7/25/2008 2:00:00 AM Last Editorial Review: 7/25/2008 ... Source: www.ctv.ca --- 12 days ago
Certain cultures and enclaves of people tend to live longer than others. Follow their lead and you might, too. ... Source: www.moreover.com --- 4 days ago
Nature Jul 21 2008 3:02PM GMT ... Source: www.naturalnews.com --- 4 hours ago
(NaturalNews) Sticking more closely to a Mediterranean diet may lead to a longer life, according to a new study published in the Archives of Internal Medicine . The researchers say that the study is the first to examine a connection between the diet and mortality in a U.S. population. Researchers examined data on more than 160,000 women and 200,000 men who had filled out detailed questionnaires about their eating habits, weight, age, smoking status and other factors known to affect health. The researchers then ranked participants based on how closely they held to either a traditional Mediterranean diet or an alternate Mediterranean diet. Participants scored higher for adherence to a traditional Mediterranean diet if they ate more fruits and nuts, grains, beans, fish and vegetables (excluding potatoes), and if they ate less dairy, meat or saturated fat. Those who drank a moderate amount of alcohol, defined as five to 25 grams per day for women and 10 to 50 grams per day for men, also scored higher. The alternative Mediterranean diet was scored similarly, but included only whole (not refined) grains, did not include dairy products, counted fruits and nuts separately, used the same alcohol standard for men and women, and deducted points for meat only if it was red or processed. The people who stuck most closely to either Mediterranean diet were significantly less likely to die during the first five years after the surveys were taken. Amo ... Source: myiris.com --- 4 days ago
Author: P.V. Subramanyam This is not a debate on whether you will live long or not live long. It is simple and easier to assume that you will live long - pretty long if you ask me. If your grandparents are pushing 85, your father is in his 2nd innings, but still holding a job at the age of 64 years and you are in your late 30s or early 40s, come to the world of Longevity. Most of the ``killer`` diseases have been eradicated or a cure found for.... ... Source: www.videogamer.com --- 1 day ago
Sony is working on a ten-year lifecycle for PS3, but Hirai isn't sure how long the Xbox 360 will be around. ... Source: www.wacotrib.com --- 2 days ago
By Wendy Gragg ... Source: www.watsonwyatt.com --- 2 days ago
The Pension Regulator's announcement that it has decided to delay the introduction of changes to the way Longevity is treated in the scheme funding regime is the right change but will be at the wrong time for some, according to Watson Wyatt. [Europe] ... Source: sportspyder.com --- 1 day ago
... er restricted free agents because they will have $60 million tied up between Paul Pierce , Ray Allen and Kevin Garnett next year, and a team can match whatever Boston ... ... Source: www.topix.com --- 20 hours ago
' In the 25 seasons Bear Bryant was at Alabama, Vanderbilt went through six head football coaches. ... Find more results for Longevity on RSSMicro.com |
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