Liver Cirrhosis

Source: news.yahoo.com --- 49 days ago
HealthDay - THURSDAY, June 5 (HealthDay News) -- Diabetes doubles the risk of Liver cancer in patients with chronic hepatitis C with advanced fibrosis, or Cirrhosis, a Dutch study reports. ...

Source: menshealth.about.com --- 24 days ago
Cirrhosis of the Liver is more common in men than women. There are a number of diseases that cause Cirrhosis but the most common are hepatitis C and alcohol abuse. One of the problems with Cirrhosis of the Liver is that signs and symptoms may not appear until the disease is quite advanced. ...

Source: www.ncbi.nlm.nih.gov --- 49 days ago
Related Articles Characterization of virus-specific T-cell immunity in Liver allograft recipients with HCV-induced Cirrhosis. Am J Transplant. 2008 Jun;8(6):1214-20 Authors: Bharat A, Barros F, Narayanan K, Borg B, Lisker-Melman M, Shenoy S, Lowell J, Crippin J, Chapman W, Mohanakumar T Recurrent hepatitis C infection (HCV) following Liver transplantation causes accelerated allograft Cirrhosis. Here we characterized HCV-specific immunity in adult Liver transplant recipients (n = 74) with and without allograft Cirrhosis. Patients were divided into hepatic inflammation/no Cirrhosis (METAVIR scores 0-2, HIN) and hepatic Cirrhosis (score 3-4, HFC). As control, 20 normal subjects and 10 non-HCV Liver transplant patients were included. Twenty-five different serum cytokines were analyzed using LUMINEX. Frequency of T-cells specific to HCV-derived proteins (NS3, NS4, NS5, Core) was characterized using ELISPOT immunoassays. There was no difference in clinical characteristics between HIN (n = 49) and HFC (n = 25) groups. HIN group had high serum IFN-gamma and IL-12 while HFC demonstrated elevated IL-4, IL-5 and IL-10 (p < 0.01). HCV (NS3, NS4, NS5, Core)-specific IFN-gamma-producing CD4+ T-cells were elevated in the HIN group whereas the HFC patients showed predominance of HCV-specific IL-5 and IL-10-producing CD4+ T-cells. CONCLUSIONS: Lack of HCV-specific Th1-type T-cell immunity is observed in Liver transplant recipients with advanced allograf ...

Source: www.moreover.com --- 50 days ago
THURSDAY, June 5 (HealthDay News) -- Diabetes doubles the risk of Liver cancer in patients with chronic hepatitis C with advanced fibrosis, or Cirrhosis, a Dutch study reports. ...

Source: www.ncbi.nlm.nih.gov --- 5 days ago
Autologous Infusion of Expanded Mobilized Adult Bone Marrow-Derived CD34+ Cells Into Patients With Alcoholic Liver Cirrhosis. Am J Gastroenterol. 2008 Jun 30; Authors: Pai M, Zacharoulis D, Milicevic MN, Helmy S, Jiao LR, Levičar N, Tait P, Scott M, Marley SB, Jestice K, Glibetic M, Bansi D, Khan SA, Kyriakou D, Rountas C, Thillainayagam A, Nicholls JP, Jensen S, Apperley JF, Gordon MY, Habib NA OBJECTIVES: Recent advances in regenerative medicine, including hematopoietic stem cell (HSC) transplantation, have brought hope for patients with severe alcoholic Liver Cirrhosis (ALC). The aim of this study was to assess the safety and efficacy of administering autologous expanded mobilized adult progenitor CD34+ cells into the hepatic artery of ALC patients and the potential improvement in the Liver function. METHODS: Nine patients with biopsy-proven ALC, who had abstained from alcohol for at least 6 months, were recruited into the study. Following granulocyte colony-stimulating factor (G-CSF) mobilization and leukapheresis, the autologous CD34+ cells were expanded in vitro and injected into the hepatic artery. All patients were monitored for side effects, toxicities, and changes in the clinical, hematological, and biochemical parameters. RESULTS: On average, a five-fold expansion in cell number was achieved in vitro, with a mean total nucleated cell count (TNCC) of 2.3 x 10(8) pre infusion. All patients tolerated the procedure well, and the ...

Source: www.ncbi.nlm.nih.gov --- 26 days ago
Related Articles [Acute renal failure in patients with Liver Cirrhosis--what to do? An update] MMW Fortschr Med. 2008 Apr 10;150 Suppl 1:22-6 Authors: Gundling F, Gülberg V, Schepp W, Mann J A lot of patients suffering from Liver Cirrhosis show a decreased renal perfusion and glomerular filtration rate. An impaired renal function is the result of complex e.g. hemodynamic disturbances, resulting of the chronic Liver disease. This explains its disposition to renal dysfunction and the higher incidence of acute renal failure in Liver Cirrhosis. In the case of renal failure hepatorenal syndrome, apart from prerenal, renal and postrenal causes, should be included in the differential diagnosis especially when signs of portal hypertension are apparent regarding its high mortalityand fatal prognosis requiring an immediate therapeutically approach. Special attention must be due to preventive strategies to avoid renal deterioration. This includes simple steps e.g. a careful election of medication but also an adequate therapy of infection-associated complications in patients with Liver Cirrhosis. PMID: 18540328 [PubMed - indexed for MEDLINE] ...

Source: www.ncbi.nlm.nih.gov --- 42 days ago
Related Articles Heart transplantation in patients with Liver Cirrhosis. Eur J Cardiothorac Surg. 2008 Jun 5; Authors: Hsu RB, Chang CI, Lin FY, Chou NK, Chi NH, Wang SS, Chu SH Objective: Liver Cirrhosis is considered to be a contraindication to heart transplantation. However, the clinical outcome of heart transplantation in patients with Liver Cirrhosis has not been reported. Here, we sought to evaluate the clinical outcome of heart transplantation in cirrhotic patients. Methods: Data were collected by retrospective chart review. Patients with Liver Cirrhosis at the time of transplantation were included. Results: Between 1987 and 2007, 12 patients with Liver Cirrhosis underwent heart transplantation at the authors' hospital. Diagnosis of Liver Cirrhosis was based on preoperative abdominal sonography in five, autopsy in five, and laparotomy in two patients. Causes of heart failure were dilated cardiomyopathy in four, coronary artery disease in three, congenital heart disease in three and valvular heart disease in two patients. Causes of Liver Cirrhosis were alcoholism in two, cardiac in seven, and unknown in three patients. The Child classification was class A in three, class B in five and class C in four patients. Overall, the hospital mortality rate was 50% and major in-hospital complications occurred in nine patients (75%). Patients with non-cardiomyopathy diagnosis, previous sternotomy, and massive ascites had a high hospital mor ...

Source: www.ncbi.nlm.nih.gov --- 31 days ago
Related Articles Successful rituximab monotherapy for API2-MALT1 fusion positive primary mucosa-associated lymphoid tissue lymphoma of the transverse colon in a patient with Liver Cirrhosis. Scand J Gastroenterol. 2008;43(6):761-4 Authors: Yamada M, Kawahara H, Shiroeda H, Tsuchishima M, Masaki Y, Sato K, Takase S PMID: 18569996 [PubMed - in process] ...

Source: www.ncbi.nlm.nih.gov --- 49 days ago
Related Articles Renal excretion of water and antidiuretic substances in patients with hepatic Cirrhosis and rats with dietary Liver injury. Endocrinology. 1949 Jan;44(1):76-82 Authors: HALL CA, FRAME B, DRILL VA PMID: 18107551 [PubMed - indexed for MEDLINE] ...

Source: www.ncbi.nlm.nih.gov --- 25 days ago
Impact of occult hepatitis B virus infection and prior hepatitis B virus infection on development of hepatocellular carcinoma in patients with Liver Cirrhosis due to hepatitis C virus. Scand J Gastroenterol. 2008;43(7):849-56 Authors: Adachi S, Shibuya A, Miura Y, Takeuchi A, Nakazawa T, Saigenji K Objective. Although hepatitis B virus (HBV) DNA can be detected in Liver or sera of patients without serum hepatitis B surface antigen (HBsAg), its clinical relevance in hepatocarcinogenesis remains controversial. This observational cohort study was conducted to clarify the risk factors, including the presence of serum HBV DNA and hepatitis B core antibody (anti-HBc), for hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV)-related Liver Cirrhosis (LC). Material and methods. The study comprised 123 patients with LC due to HCV, and negative for HBsAg. The risk factors for HCC development were analyzed by univariate and multivariate analysis. Serum samples were assayed for HBV DNA using real-time polymerase chain reaction. Results. Serum HBV DNA was detectable in 14 patients (11.4%) and serum anti-HBc in 96 (78.0%). During the follow-up period (mean 53.3 months), 80 patients (65.0%) developed HCC. The cumulative HCC development rate was significantly higher in the anti-HBc-positive group than in the anti-HBc-negative group (p=0.0039), but did not differ between the serum HBV DNA-positive and -negative groups (p=0.8570). The ...

Source: www.fwicki.com --- 48 days ago
THURSDAY, June 5 (HealthDay News) -- Diabetes doubles the risk of Liver cancer in patients with chronic hepatitis C with advanced fibrosis, or Cirrhosis, a Dutch study reports. Researchers at the Erasmus MC University Medical Center in Rotterdam ... ...

Source: www.fwicki.com --- 48 days ago
Over years or decades, chronic hepatitis B virus infection can lead to the development of advanced Liver disease, including Cirrhosis and hepatocellular carcinoma . ...

Source: www.e-healthsource.com --- 43 days ago
Chances doubled, especially for older males, Dutch study finds ...

Source: www.fwicki.com --- 4 days ago
Cirrhosis: Caring for Patients with End-stage Liver Failure Lynn A. Kelso RN, APRN, BC, MSN, FCCM The Nurse Practitioner: The American Journal of Primary Health Care July 2008 Volume 33 Number 7 Pages 24 - 30 ... ...

Source: www.fwicki.com --- 23 days ago
Dear Dr. Donohue: Please write about the Liver. My daughter has Cirrhosis. She has never drunk alcohol or done drugs. They can't find out what caused it. Anything you can tell us would be really appreciated. M.R. Dear M.R.: The Liver is the body's ... ...

Source: www.pkids.org --- 50 days ago
Copyright © 2008 ScoutNews LLC. All rights reserved. THURSDAY, June 5 (HealthDay News) -- Diabetes doubles the risk of Liver cancer in patients with chronic hepatitis C with advanced fibrosis, or Cirrhosis, a Dutch study reports. ...

Source: www.pkids.org --- 50 days ago
THURSDAY, June 5 (HealthDay News) -- Diabetes doubles the risk of Liver cancer in patients with chronic hepatitis C with advanced fibrosis, or Cirrhosis, a Dutch study reports. ...

Source: www.medicalnewstoday.com --- 3 days ago
Patients with the hepatitis C virus who receive a Liver from a donor older than age 60 do not experience a higher rate of transplant failure, death, or recurrent disease in the following five years, according to a study published in the July issue of Archives of Surgery. The most common reason for Liver transplants among adults in the United States is Cirrhosis of the Liver caused by the hepatitis C viral infection. ...

Source: forums.studentdoctor.net --- 11 days ago
Okay, so while reading for my last clerkship of third year, family medicine; I read in Blueprints Clinical Cases (copyright 2007) that "Hepatitis C has surpassed alcoholic Liver disease as the most common cause of Cirrhosis in the US (26%). ... ...

Source: mysticwicks.com --- 9 days ago
I have not really done this before, usually I try to tackle things on my own. A week ago I received a call from my doctor and he informed me that the pain medications that I have been taking all along have pushed me into a place that scares me. I have been diagnosed with Cirrhosis of the Liver. ... ...