Leukemia

Source: news.yahoo.com --- 6 days ago
HealthDay - MONDAY, Oct. 6 (HealthDay News) -- A new technique may help doctors diagnose a rare form of Leukemia in a matter of hours instead of weeks, researchers say. ...

Source: news.yahoo.com --- 2 days ago
More than $53,000 was raised last week at the South Carolina Chapter of the Leukemia & Lymphoma Society's annual Light the Night Walk. ...

Source: articles.moneycentral.msn.com --- 4 days ago
Companies' arthritis drug helps patients with stubborn strains of blood cancer. ...

Source: www.ncbi.nlm.nih.gov --- 10 days ago
Related Articles Molecular biology of BCR-ABL1-positive chronic myeloid Leukemia. Blood. 2008 Sep 30; Authors: Quintas-Cardama A, Cortes J Chronic myelogenous Leukemia (CML) has been regarded as the paradigmatic example of a malignancy defined by a unique molecular event, the BCR-ABL1 oncogene. Decades of research zeroing in on the role of BCR-ABL1 kinase in the pathogenesis of CML have culminated in the development of highly efficacious therapeutics which, like imatinib mesylate, target the oncogenic kinase activity of BCR-ABL1. In recent years, most research efforts in CML have been devoted to developing novel tyrosine kinase inhibitors (TKIs) as well as to elucidating the mechanisms of resistance to imatinib and other TKIs. Yet, primordial aspects of the pathogenesis of CML such as the mechanisms responsible for the transition from chronic phase to blast crisis, the causes of genomic instability and faulty DNA repair, the phenomenon of stem cell quiescence, the role of tumor suppressors in TKI resistance and CML progression, or the cross-talk between BCR-ABL1 and other oncogenic signaling pathways still remain poorly understood. Herein, we synthesize the most relevant and current knowledge on such areas of the pathogenesis of CML. PMID: 18827185 [PubMed - as supplied by publisher] ...

Source: www.ncbi.nlm.nih.gov --- 1 day ago
Outcome of adults with acute lymphocytic Leukemia after second salvage therapy. Cancer. 2008 Oct 7; Authors: O'Brien S, Thomas D, Ravandi F, Faderl S, Cortes J, Borthakur G, Pierce S, Garcia-Manero G, Kantarjian HM BACKGROUND.: The outcome of adults with acute lymphocytic Leukemia (ALL) who undergo second salvage therapy has been characterized poorly. This is important with regard to investigational approaches aimed at helping this subset of patients. The objectives of the current study were to predict outcomes and determine the prognostic factors associated with second salvage therapy in patients with ALL. METHODS.: In this study, 288 patients were analyzed who received second salvage therapy for ALL at the authors' institution. RESULTS.: Overall, 53 patients (18%) achieved a complete response (CR). The median remission duration was 7 months and the median survival was 3 months. In multivariate analysis, prognostic factors that were associated independently with achieving CR were duration of first CR and platelet count. Patients with a first CR <36 months and platelet counts <50 x 10(9)/L had an expected CR rate of 7%. In multivariate analysis, prognostic factors that were associated independently with survival were duration of first CR, percentage bone marrow blasts, platelet count, and albumin level. The expected 12-month survival rates for patients with 0 or 1, 2, 3, or 4 adverse factors were 33%, 14%, 8%, and 0%, respectively. A ...

Source: www.ncbi.nlm.nih.gov --- 7 days ago
Related Articles Respiratory Viral Infections in Children With Leukemia. Pediatr Infect Dis J. 2008 Oct 1; Authors: Koskenvuo M, Möttönen M, Rahiala J, Saarinen-Pihkala UM, Riikonen P, Waris M, Ziegler T, Uhari M, Salmi TT, Ruuskanen O BACKGROUND:: Respiratory viruses occur frequently in the community and are a common cause of fever in children. Data on respiratory viral infections in children with cancer are limited. METHODS:: A long-term, prospective, multicenter study was carried out in Finland searching for respiratory viruses in febrile children with Leukemia. For this purpose, 138 febrile episodes in 51 children with Leukemia were analyzed. Twelve types of respiratory viruses were searched for by viral culture, antigen detection, and polymerase chain reaction tests. RESULTS:: Evidence of a respiratory viral infection was found in 61 of 138 febrile episodes (44%), accounting for an incidence of 0.8 (range, 0-2.4) per person year at risk during the treatment of Leukemia. The most common viruses detected were rhinovirus (22%), respiratory syncytial virus (11%), human bocavirus (5%), and influenza A virus (4%). Dual viral infections were detected in 12 cases (9%). Half of the children had respiratory symptoms with cough being the most common symptom. Two children developed pneumonia. The mean duration of fever was 2.6 (SD 1.7) days in children with respiratory viral infection and 2.1 (SD 1.3) days in children without evidence of vir ...

Source: www.ncbi.nlm.nih.gov --- 8 days ago
Related Articles [Guidelines for the management of dasatinib (Sprycel)-induced side effects in chronic myelogenous Leukemia and Philadelphia positive acute lymphoblastic leukemias] Bull Cancer. 2008 Oct 1;95(9):805-11 Authors: Cony-Makhoul P, Bergeron A, Corm S, Dubruille V, Rea D, Rigal-Huguet F, Nicolini FE Dasatinib (Sprycel) is a new-targeted therapy used since 2005 in the treatment of chronic myelogenous Leukemia and de novo Philadelphia positive acute lymphoblastic leukaemia patients, intolerant or resistant to imatinib. Despite its high efficacy in such patients in terms of hematologic, cytogenetic and molecular responses, the onset of frequent and sometimes serious side effects particularly in advanced phase patients, especially myelosuppressions and pleural effusions, may impair optimal administration of the drug. Recently, dasatinib dose optimisation in chronic-phase has reduced the incidence of such adverse events without modification of the efficacy, however, their optimal overall management can efficiently reduce their severity and minimize their impact on disease response. Hereby, we attempted to propose a series of guidelines that might be of help in daily practice, in order to control properly these side effects. PMID: 18829412 [PubMed - in process] ...

Source: chicago.metromix.com --- 2 days ago
A fundraiser for Leukemia research includes draft beers, wine, select cocktails, a DJ and live music by Loaded and Dr. V. ...

Source: www.baltimoresun.com --- 4 days ago
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Source: www.baltimoresun.com --- 3 days ago
Re: Lax blogger John Weaver talks to Loyola women's coach Jen Adams and John Valenti, whose son Matthew has Acute Lymphocytic Leukemia, about their involvement with the tournament, which will be held Oct. 11 at St. Paul's School in Brooklandville ...

Source: www.medicalnewstoday.com --- 19 hours ago
Genentech, Inc. (NYSE: DNA) and Biogen Idec (Nasdaq: BIIB) today announced that a global Phase III study of Rituxan® (rituximab) in combination with fludarabine and cyclophosphamide chemotherapy met its primary endpoint of improving progression-free survival (PFS), as assessed by investigators, in patients with previously treated CD20-positive chronic lymphocytic Leukemia (CLL) compared to chemotherapy alone. There were no new or unexpected safety signals reported in the study. ...

Source: www.medicalnewstoday.com --- 6 days ago
As part of a comprehensive R&D effort to develop an analytic tool to assist in accurately identifying Leukemia stem cells, Oerlikon Leybold Vacuum is supporting the StemSpec R&D project at the University of Toronto with a TURBOVAC SL turbomolecular vacuum pump and a fore vacuum pump, and advising researchers about the use of the pumps. ...

Source: weblogs.baltimoresun.com --- 3 days ago
The 11th-annual Price Modern Lacrosse for Leukemia Fall Invitational Tournament will be held this Saturday, Oct. 11, from 8:30 a.m. to 4:30 p.m. at St. Paul’s School in Brooklandville, Md. The tournament has long been a first-rate fall ball event for men’s college teams. This year women’s teams will join the fun, and all for a great cause. The Leukemia & Lymphoma Society (LLS) is the world’s largest voluntary health organization dedicated to funding blood cancer research, education, and patient services. Unfortunately, more than 894,000 Americans currently have blood cancers, many of them children. Each team participating will play in honor of a local youth ambassador who is a survivor of, or is currently undergoing treatment for a blood cancer. These youngsters will serve as “honorary captains” for each team and will spend the day with their respective squads on the team bench. The tournament has raised over $915,000 for research and patient services over 10 years on behalf of the Maryland Chapter of LLS. The money goes toward its mission to cure Leukemia, lymphoma, Hodgkin’s disease, and myeloma, and to improve the quality of life of patients and their families. Spectator admission is $5 per person or $20 per car (parking included). The eight women’s teams participating in the event are Towson, Johns Hopkins, Maryland, Loyola, George Mason, Penn State, Rutgers, and Louisville, while the men’s teams will be Towson, UMBC, Delaware ...

Source: upcoming.yahoo.com --- 5 days ago
Date: Tuesday, October 7, 2008 Time: 5:30 pm to 8:30 pm Place: Temple, 540 Howard Street, San Francisco, CA Ticket: $20 before October 7, 2008/$25 after October 7, 2008 and at the door Join us for a special event. IPE is partnering with the San Francisco Chamber of Commerce's Business Alliance and BNI's San Francisco Chapters to benefit The Leukemia & Lymphoma Society. Price of your ticket includes appetizers and drink specials. For more information about the Chamber's Business Allliance Program see: http://www.sfchamber.com/programs_business_alliance.htm For more information about San Francisco Chapters of BNI see: http://www.bni-sfbay.com/ For more information about The Leukemia & Lymphoma Society see: http://www.Leukemia.org/hm_lls ...

Source: www.healthboards.com --- 6 days ago
Hello, I am new to this site. I have pernicious anemia and Haemochromotosis. On my mother's side of the family, both of these were common with 4 immediate members of my mothers family dying of Leukemia (including my mother). Both my sisters had... ...

Source: www.rgj.com --- 17 hours ago
Scientists investigating the Fallon cancer cluster unveiled further results Friday about tungsten, an element found in abundance in the town where ...

Source: uneasysilence.com --- 9 days ago
No, this is not a bogus headline… Using an older Mac Pro could drastically increase your chance for Leukemia. [A French newspaper claims] that the tower’s smell is the cause and in fact, contains a few toxins, including benzene. Several forum users have noted the smell as well (anyone notice it?), and the French AppleCare acknowledged [...] ...

Source: www.rgj.com --- 4 days ago
Scientists are scheduled Friday to present the latest findings related to the Fallon cancer cluster, which has sickened 17 children and killed ...

Source: www.centredaily.com --- 5 days ago
Genentech, Inc. (NYSE:DNA) and Biogen Idec (Nasdaq:BIIB) today announced that a global Phase III study of Rituxan(R) (rituximab) in combination with fludarabine and cyclophosphamide chemotherapy met its primary endpoint of improving progression-free survival (PFS), as assessed by investigators, in patients with previously treated CD20-positive chronic lymphocytic Leukemia (CLL) compared to chemotherapy alone. There were no new or unexpected safety signals reported in the study. An independent review of the primary endpoint is being conducted for U.S. regulatory purposes. ...

Source: www.rgj.com --- 1 day ago
Scientists studying a childhood cluster in Fallon are looking for the remaining seven out of 17 families whose children were diagnosed with Leukemia in an epidemic that began in 1997. ...