Genome

Source: news.bbc.co.uk --- 4 days ago
The county council is to discuss giving support to a new £13.5m Genome research centre in Norwich. ...

Source: www.moreover.com --- 2 days ago
ScienceDaily (Oct. 8, 2008) ? Researchers have decoded the Genome of a malaria parasite that has a host range from monkeys to man. Identified originally in monkeys, the parasite was first reported in a human infection just over 40 years ago. ...

Source: www.moreover.com --- 4 days ago
Extract not available. ...

Source: www.ncbi.nlm.nih.gov --- 5 days ago
Related Articles Shaping a bacterial Genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae. Proc Natl Acad Sci U S A. 2008 Oct 2; Authors: Brochet M, Rusniok C, Couvé E, Dramsi S, Poyart C, Trieu-Cuot P, Kunst F, Glaser P Bacterial populations are subject to complex processes of diversification that involve mutation and horizontal DNA transfer mediated by transformation, transduction, or conjugation. Tracing the evolutionary events leading to genetic changes allows us to infer the history of a microbe. Here, we combine experimental and in silico approaches to explore the forces that drive the Genome dynamics of Streptococcus agalactiae, the leading cause of neonatal infections. We demonstrate that large DNA segments of up to 334 kb of the chromosome of S. agalactiae can be transferred through conjugation from multiple initiation sites. Consistently, a Genome-wide map analysis of nucleotide polymorphisms among eight human isolates demonstrated that each chromosome is a mosaic of large chromosomal fragments from different ancestors suggesting that large DNA exchanges have contributed to the Genome dynamics in the natural population. The analysis of the resulting genetic flux led us to propose a model for the evolutionary history of this species in which clonal complexes of clinical importance derived from a single clone that evolved by exchanging large chromosomal regions with more distantly relat ...

Source: www.ncbi.nlm.nih.gov --- 6 days ago
Related Articles Evolutionary origins of human apoptosis and Genome-stability gene networks. Nucleic Acids Res. 2008 Oct 2; Authors: Castro MA, Dalmolin RJ, Moreira JC, Mombach JC, de Almeida RM Apoptosis is essential for complex multicellular organisms and its failure is associated with Genome instability and cancer. Interactions between apoptosis and Genome-maintenance mechanisms have been extensively documented and include transactivation-independent and -dependent functions, in which the tumor-suppressor protein p53 works as a 'molecular node' in the DNA-damage response. Although apoptosis and Genome stability have been identified as ancient pathways in eukaryote phylogeny, the biological evolution underlying the emergence of an integrated system remains largely unknown. Here, using computational methods, we reconstruct the evolutionary scenario that linked apoptosis with Genome stability pathways in a functional human gene/protein association network. We found that the entanglement of DNA repair, chromosome stability and apoptosis gene networks appears with the caspase gene family and the antiapoptotic gene BCL2. Also, several critical nodes that entangle apoptosis and Genome stability are cancer genes (e.g. ATM, BRCA1, BRCA2, MLH1, MSH2, MSH6 and TP53), although their orthologs have arisen in different points of evolution. Our results demonstrate how Genome stability and apoptosis were co-opted during evolution recruiting genes t ...

Source: blog.wired.com --- 4 days ago
This story has been updated. A biotech startup company promises to decipher the human Genome for $5,000 -- a price tag that could literally change the world, making high-resolution genetic scans available to relatively low-budget laboratories, and literally reshaping the... ...

Source: www.lib.ncsu.edu --- 3 days ago
Mouse Genome Informatics (MGI) provides free, publicly available access to integrated data on the genetics, genomics and biology of the laboratory mouse. Trainers from MGI are coming to NCSU on Wednesday, November 5th for a workshop from 1:30-3:30 pm on main campus in the DH Hill Library's ITTC Lab 2 ( 2nd floor of the East Wing ). The two-hour workshop consists of a 20-30 minute presentation followed by 90 minutes of hands-on training in which you will explore the MGI database in depth and will use MGI to: find mouse models of human disease; locate mouse genotypes associated with a specific phenotype; identify suppliers of mice carrying a mutation in a gene of interest; find gene expression assays and images; view terms describing the molecular function, biological process and cellular component of a gene, and retrieve a list of genes annotated with a specific Gene Ontology (GO) term; identify single nucleotide polymorphisms (SNPs) and PCR polymorphisms specific to selected mouse strains; locate suppliers of BAC or cDNA clones; download MGI data or perform batch queries. For more information about this workshop, or to register, contact Eleanor Smith at eleanor_smith@ncsu.edu . ...

Source: www.moreover.com --- 4 days ago
USAgNet Oct 6 2008 1:03PM GMT ...

Source: www.technologyreview.com --- 4 days ago
A new sequencing service could change the face of human genomics. ...

Source: www.moreover.com --- 6 days ago
Financials.com Oct 5 2008 12:33AM GMT ...

Source: www.moreover.com --- 3 days ago
Journal of the American Medical Association Oct 7 2008 9:08PM GMT ...

Source: www.moreover.com --- 7 days ago
Red Orbit Oct 3 2008 6:00PM GMT ...

Source: sciencenow.sciencemag.org --- 8 days ago
Researchers make significant progress toward sequencing highly complex crop ...

Source: www.sciencedaily.com --- 1 day ago
In research aimed at addressing a global epidemic, a team of scientists from around the world has cracked the genetic code for the parasite that is responsible for up to 40 percent of the 515 million annual malaria infections worldwide. Scientists have deciphered the complete genetic sequence of the parasite Plasmodium vivax, the leading cause of relapsing malaria, and compared it with the genomes of other species of malaria parasites. ...

Source: www.moreover.com --- 1 day ago
Yahoo! India Oct 9 2008 6:31PM GMT ...

Source: forums.thestranger.com --- 3 days ago
In some ways I'm a technological Luddite. I've never been an early adopter of anything. So it's eight years on and I'm just discovering the wonders of the Music Genome Project. Oh, I'd heard about it, but never had experienced it. So now that I've created a couple of Pandora stations I'm... ...

Source: www.obbec.com --- 38 minutes ago
According to an announcement from Wellcome Trust Sanger Institute, a team of researchers at the institute have decoded the Genome of a malaria parasite that has a host range from monkeys to man. Identified originally in monkeys, the parasite was first reported in a human infection just over 40 years ago. ...

Source: www.thehorse.com --- 1 day ago
The latest Horse Course from the University's of Kentucky's Livestock Disease Diagnostic Center and Gluck Equine Research Center and presented by Fort Dodge Animal Health is now available for viewing on TheHorse.com. This presentation is on the Equine... ...

Source: www.computerworlduk.com --- 4 days ago
We're getting close : ...

Source: scienceblogs.com --- 4 days ago
Dawn of Low-Price Mapping Could Broaden DNA Uses in The New York Times . So of course I checked in on Genetic Future : There's an important message here between the lines: as technology drives the price of sequencing down, massive competition between platforms and service providers will almost certainly drive down the profit margins of sequencing providers. The real money will then be in providing sophisticated, up-to-date and easily understandable Genome interpretation services. The best interpretations will come from the companies with the largest databases of genetic information, and with expertise in putting that complex information in the appropriate context for lay consumers.... This kind of reminds me of many open source business models. Read the comments on this post... ...