Genetics

Source: articles.moneycentral.msn.com --- 2 days ago
Myriad Genetics sinks on Flurizan news. ...

Source: news.yahoo.com --- 4 days ago
Reuters - Myriad Genetics Inc said it will stop developing its drug for Alzheimer's disease after a late-stage trial of the drug, Flurizan, failed to meet primary goals. ...

Source: blog.wired.com --- 8 days ago
"Witches' broom," "frosty pod," and "black pod" may sound like exotic plants out of a fantasy novel, but they're diseases that are all too real to cacao farmers all over the world. Cacao, which is of course the chief ingredient... ...

Source: alcoholism.about.com --- 20 hours ago
New research shows that genetic factors may determine those at increased risk of developing liver disease. ...

Source: www.nytimes.com --- 5 days ago
James P. Evans hopes to demystify all of science and, specifically, Genetics. ...

Source: www.moreover.com --- 4 days ago
According to a study from the United States, 'Because of their high in the general , variants that determine susceptibility to environmental exposures may contribute greatly to the development of occupational diseases in the setting of specific ...

Source: www.moreover.com --- 4 days ago
'Branchio-oculo-facial (BOFS) is a rare autosomal-dominant cleft palate-craniofacial disorder with variable expressivity. ...

Source: www.ncbi.nlm.nih.gov --- 4 days ago
Related Articles Molecular Genetics of attention. Ann N Y Acad Sci. 2008;1129:200-12 Authors: Bellgrove MA, Mattingley JB The sequencing of the human genome and the identification of a vast array of DNA polymorphisms has afforded cognitive scientists with the opportunity to interrogate the genetic basis of cognition with renewed vigor. The extant literature on the molecular Genetics of sustained and spatial attention is reviewed herein. Advances in our understanding of the neural substrates of sustained and spatial attention arising from the cognitive neurosciences can help guide putative linkages in cognitive Genetics. In line with catecholamine models of sustained attention, associations have been reported between sustained attention and allelic variation in the dopamine beta hydroxylase gene (DBH), the dopamine D2 and D4 receptor genes (DRD2; DRD4) and the dopamine transporter gene (DAT1). Much evidence implicates the cholinergic system in spatial attention. Accordingly, individual differences in spatial attention have been associated with variation in an alpha-4 cholinergic receptor gene (CHRNA4). APOE-epsilon4 allele dosage has been shown to influence the speed of attentional reorienting in independent samples of nonaffected individuals. Preliminary evidence in both healthy children and children with attention deficit hyperactivity disorder (ADHD) suggests and association with variants of the DAT1 gene and the control of spatial a ...

Source: www.ncbi.nlm.nih.gov --- 2 hours ago
Related Articles Complex Trait Genetics The Role of Mechanistic "Intermediate Phenotypes" and Candidate Genetic Loci. J Am Coll Cardiol. 2008 Jul 8;52(2):166-168 Authors: Rao F, Zhang L, O'Connor DT PMID: 18598897 [PubMed - as supplied by publisher] ...

Source: www.ncbi.nlm.nih.gov --- 5 hours ago
Related Articles Neuroimaging, Genetics and the treatment of nicotine addiction. Behav Brain Res. 2008 Jun 5; Authors: Ray R, Loughead J, Wang Z, Detre J, Yang E, Gur R, Lerman C Advances in neuroimaging and genomics provide an unprecedented opportunity to accelerate medication development for nicotine dependence and other addictions. Neuroimaging studies have begun to elucidate the functional neuroanatomy and neurochemistry underlying effects of nicotine and nicotine abstinence. In parallel, genetic studies, including both candidate gene and genome-wide association approaches, are identifying key neurobiological targets and pathways important in addiction to nicotine. To date, only a few neuroimaging studies have explored effects of nicotine or abstinence on brain activity as a function of genotype. Most analyses of genotype are retrospective, resulting in small sample sizes for testing effects of the minor alleles for candidate genes. The purpose of this review is to provide an outline of the work in neuroimaging, Genetics, and nicotine dependence, and to explore the potential for increased integration of these approaches to improve nicotine dependence treatment. PMID: 18599130 [PubMed - as supplied by publisher] ...

Source: www.moreover.com --- 5 days ago
A CONVERSATION WITH JAMES EVANS James Evans, a physician and molecular biologist, teaches Genetics at the University of North Carolina School of Medicine. ...

Source: www.theoptionsinsiders.com.com --- 4 days ago
Options Update for JP Morgan Chase (JPM) and Myriad Genetics (MYGN) ...

Source: www.ncbi.nlm.nih.gov --- 4 hours ago
Related Articles A single nucleotide polymorphism alters the sequence of SP1 binding site in the adiponectin promoter region and is associated with diabetic nephropathy among type 1 diabetic patients in the Genetics of Kidneys in Diabetes Study. J Diabetes Complications. 2008 Jul 2; Authors: Zhang D, Ma J, Brismar K, Efendic S, Gu HF OBJECTIVE: The adiponectin promoter single nucleotide polymorphism (SNP) -11391G/A is found to be associated with nephropathy in type 1 diabetic (T1D) patients among Danish, but not French, Finnish, and Swedish populations. In the present study, we identified the binding sites for transcriptional factors in the adiponectin promoter region and also evaluated the association between adiponectin promoter polymorphisms and diabetic nephropathy (DN) in T1D patients. MATERIALS AND METHODS: Three adiponectin promoter SNPs, including -11377C/G, -11391G/A, and -11426A/G, were genotyped with dynamic allele-specific hybridization. The subjects included 1177 American T1D patients (622 females/555 males) with or without DN. All patients are of European descent and selected from the Genetics of Kidneys in Diabetes (GoKinD) study. RESULTS: We identified four binding sites of transcriptional stimulatory protein (SP1) in the adiponectin putative promoter and found that the G allele of SNP -11377C/G altered the sequence for one of the SP1 binding sites. This polymorphism was significantly associated with DN in female T1D pa ...

Source: blog.seattlepi.nwsource.com --- 4 days ago
VLST Corp., the heavily funded but under-the-radar Seattle-based biotech company, has hired a top executive from Seattle Genetics to be its chief scientific officer. ...

Source: www.cdc.gov --- 2 days ago
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Source: www.miamiherald.com --- 16 hours ago
When West Boca Raton High cheerleader Stephanie Kuleba died in March after outpatient surgery, geneticists Jeffery Vance and Margaret Pericak-Vance had a suspicion. ...

Source: www.medicinenet.com --- 4 days ago
Title: Genetics, Environment Shape Sexual Behavior Category: Health News Created: 7/1/2008 2:00:00 AM Last Editorial Review: 7/1/2008 ...