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Source: runway.blogs.nytimes.com --- 9 days ago
The runway at Alexander McQueen’s spring 2009 collection. (Christophe Ena/Associated Press) At the back of Alexander McQueen’s rather brilliant show tonight, near a modest assortment of stuffed African animals, was the projected image of a large roving eyeball. It had replaced an image of earth seen from outer space, so the inference was that we are [...] ... Source: www.ncbi.nlm.nih.gov --- 12 days ago
Related Articles Clinical, agricultural, and Evolutionary biology of myostatin: a comparative review. Endocr Rev. 2008 Aug;29(5):513-34 Authors: Rodgers BD, Garikipati DK The discovery of myostatin and our introduction to the "Mighty Mouse" over a decade ago spurred both basic and applied research and impacted popular culture as well. The myostatin-null genotype produces "double muscling" in mice and livestock and was recently described in a child. The field's rapid growth is by no means surprising considering the potential benefits of enhancing muscle growth in clinical and agricultural settings. Indeed, several recent studies suggest that blocking myostatin's inhibitory effects could improve the clinical treatment of several muscle growth disorders, whereas comparative studies suggest that these actions are at least partly conserved. Thus, neutralizing myostatin's effects could also have agricultural significance. Extrapolating between studies that use different vertebrate models, particularly fish and mammals, is somewhat confusing because whole genome duplication events have resulted in the production and retention of up to four unique myostatin genes in some fish species. Such comparisons, however, suggest that myostatin's actions may not be limited to skeletal muscle per se, but may additionally influence other tissues including cardiac muscle, adipocytes, and the brain. Thus, therapeutic intervention in the clinic or on the farm ... Source: www.ncbi.nlm.nih.gov --- 8 days ago
Related Articles Shaping a bacterial genome by large chromosomal replacements, the Evolutionary history of Streptococcus agalactiae. Proc Natl Acad Sci U S A. 2008 Oct 2; Authors: Brochet M, Rusniok C, Couvé E, Dramsi S, Poyart C, Trieu-Cuot P, Kunst F, Glaser P Bacterial populations are subject to complex processes of diversification that involve mutation and horizontal DNA transfer mediated by transformation, transduction, or conjugation. Tracing the Evolutionary events leading to genetic changes allows us to infer the history of a microbe. Here, we combine experimental and in silico approaches to explore the forces that drive the genome dynamics of Streptococcus agalactiae, the leading cause of neonatal infections. We demonstrate that large DNA segments of up to 334 kb of the chromosome of S. agalactiae can be transferred through conjugation from multiple initiation sites. Consistently, a genome-wide map analysis of nucleotide polymorphisms among eight human isolates demonstrated that each chromosome is a mosaic of large chromosomal fragments from different ancestors suggesting that large DNA exchanges have contributed to the genome dynamics in the natural population. The analysis of the resulting genetic flux led us to propose a model for the Evolutionary history of this species in which clonal complexes of clinical importance derived from a single clone that evolved by exchanging large chromosomal regions with more distantly relat ... Source: www.moreover.com --- 7 days ago
Søran Kierkegaard used to tell parables by way of doing philosophy. One went like this. An ancient Greek was asked to define religion. He asked for time to prepare an answer. ... Source: www.ncbi.nlm.nih.gov --- 9 days ago
Related Articles Evolutionary origins of human apoptosis and genome-stability gene networks. Nucleic Acids Res. 2008 Oct 2; Authors: Castro MA, Dalmolin RJ, Moreira JC, Mombach JC, de Almeida RM Apoptosis is essential for complex multicellular organisms and its failure is associated with genome instability and cancer. Interactions between apoptosis and genome-maintenance mechanisms have been extensively documented and include transactivation-independent and -dependent functions, in which the tumor-suppressor protein p53 works as a 'molecular node' in the DNA-damage response. Although apoptosis and genome stability have been identified as ancient pathways in eukaryote phylogeny, the biological evolution underlying the emergence of an integrated system remains largely unknown. Here, using computational methods, we reconstruct the Evolutionary scenario that linked apoptosis with genome stability pathways in a functional human gene/protein association network. We found that the entanglement of DNA repair, chromosome stability and apoptosis gene networks appears with the caspase gene family and the antiapoptotic gene BCL2. Also, several critical nodes that entangle apoptosis and genome stability are cancer genes (e.g. ATM, BRCA1, BRCA2, MLH1, MSH2, MSH6 and TP53), although their orthologs have arisen in different points of evolution. Our results demonstrate how genome stability and apoptosis were co-opted during evolution recruiting genes t ... Source: www.ncbi.nlm.nih.gov --- 4 days ago
Related Articles Evolutionary analysis of PHLPP1 gene in humans and non-human primates. Bioinformation. 2008;2(10):471-4 Authors: Anbazhagan P, Purushottam M, Kumar HB, Kubendran S, Mukherjee O, Brahmachari SK, Jain S, Sowdhamini R The chromosome 18q22-23 region has been shown to be implicated in bipolar disorder (BPAD) by several studies. PHLPP1 gene, in the locus (chromosome 18q22-23), is involved in circadian pathways and bears modules like 'PH domain and leucine rich repeat protein phosphatase'. This gene also contains a polyglutamine (CAG or PolyQ) repeat motif at the carboxyl terminal end. A comparative analysis of the PolyQ repeats of the PHLPP1 gene in humans, non-human primates and other species has been attempted in order to investigate the possible significance of repeat length as seen in other triplet-repeat associated diseases. Sequencing of the CAG repeat in humans and in non-human primates revealed that the CAG repeat is not polymorphic in humans; whereas, in other species it shows an area of high variability, both in length and sequence composition. Despite the conservation of circadian clock components in different species, there is remarkable diversity in the protein structure, regulation and biochemical functions of the circadian orthologs. These can be due to specific adaptations in accordance with the physiology of the particular species providing a species-specific biological advantage. PMID: 18841245 [PubMed - in ... Source: www.moreover.com --- 32 days ago
What a big month this was with many Linux releases (and not just Linux ones). The third most popular Linux distribution (along with Debian), after Red Hat and Mandrake, is SuSE. ...
Source: news.sky.com --- 6 days ago
Humans are the best they can possibly be and this is as good as it gets. ... Source: www.ft.com --- 35 days ago
Creator of new game of evolution says users can create in seconds what a Pixar animator would take hours to do ...
Source: www.nzherald.co.nz --- 6 days ago
Research from New Zealand universities suggests evolution is not necessarily reflected in an animal's appearance. Craig Millar, of Auckland University's School of Biological Sciences, said the study, which looked at gene changes... ... Source: www.moreover.com --- 20 hours ago
Inside Costa Rica Oct 12 2008 7:07PM GMT ... Source: www.moreover.com --- 5 days ago
Firstscience.com Oct 8 2008 6:09AM GMT ... Source: upcoming.yahoo.com --- 11 days ago
Facilitated by Kathia Laszlo, Alexander Laszlo and Manuel Manga Saybrook Graduate School, 747 Front St., 3rd Floor. San Francisco Join us in a learning conversation about the challenges and opportunities we face as leaders seeking to bring values and integrity to our work. If you have participated in the 3-day workshop Evolutionary Leadership for Sustainability or if you are curious about it, this event is an opportunity to (re)connect with people who are on a similar path. The conversation will engage your mind and heart in a collaborative exploration of questions that matter for you and the planet. ... Source: www.intomobile.com --- 4 days ago
The folks over at TechDigest have got a great take on a recent report that humans have hit their Evolutionary limit - they have suggested some tech upgrades for us! I’ve picked out a few of my fave ideas ideas below, but you’ll have to link over to their site to check out the full [...] ... Source: www.medicalnewstoday.com --- 4 days ago
Do Internet users scavenge the web like prehistoric hunters and gatherers? Can Darwin help us understand Internet user habits? These are the questions studied by brothers Philippe Stenstrom, PhD student at the Université de Montréal Department of Psychology, and Eric Stenstrom, PhD student in marketing at Concordia University. ... Source: www.metro.co.uk --- 7 days ago
Humans evolution has virtually reached its peak and we can expect to increase our life expectancy by a maximum of only two more years ...
Source: www.adultinsider.com --- 33 days ago
The SimCity creator goes galactic with his new... ... Find more results for Evolutionary on RSSMicro.com |
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(((Uh-oh... looks like that could kill a weekend pretty easy.))) http://www.biobloc.net/# Link: Biobloc - Welcome . ...
In the beginning Will Wright created the idea, but not the name. Now the game was formless and empty, darkness was over the deep concepts, and Wright was hovering over his small group of developers. And Wright said, "Let there be five stages in the game," and there were. And Wright said "Let the waters teem with living creatures, let birds fly above the planets, and let gamers produce them all." Wright saw all that he had made, and it was very good. And there was real-time strategy, and there was procedural animation and perhaps even firmament, though I'm not quite sure what that word means. It was the sixth year. Without a doubt Spore is a genre-busting, piece of innovative work, but is it a good game? Did Maxis create something sublime, or does Spore still needs to evolve? Loved Evolutionary Creationism : Spore's creature creator is almost worth the price of entry. Access to all of the game's creators definitely is. In Spore, Maxis delivers the gameplay but you create the backdrop. This mutual process of creation forms a living diorama. Something as fun to marvel at as it is to tinker with. A Gaming Buffet : While Space is certainly the strongest of the game's five stages, the others shouldn't be written off. The first time through, one might have the urge to rush things in their race to get to space. But once you've played through the entire game, Spore allows you to go back and play whichever stage you want as a standalone. I ...