Epilepsy

Source: us.rd.yahoo.com --- 6 days ago
HealthDay - (HealthDay News) -- People with Epilepsy are prone to injury in the event of a sudden seizure. ...

Source: news.bbc.co.uk --- 8 days ago
The death of a 10-year-old girl inspires her parents to help young Epilepsy patients across Teesside. ...

Source: www.moreover.com --- 10 days ago
TopAbstracts? in Epilepsy are the abstracts most highly rated/most read by nearly 300,000 physicians who received a Doctor's Guide? newsletter or visited a website Powered by Doctor's Guide? in the past 14 days. ...

Source: www.ncbi.nlm.nih.gov --- 13 days ago
Related Articles Seizure freedom reduces illness intrusiveness and improves quality of life in Epilepsy. Can J Neurol Sci. 2008 Jul;35(3):280-6 Authors: Poochikian-Sarkissian S, Sidani S, Wennberg R, Devins GM BACKGROUND: Chronic illnesses are associated with multiple stressors that compromise quality of life (QOL). Implicit in many of these stressors is the concept of illness intrusiveness: the disruption of lifestyles, activities, and interests due to the constraints imposed by chronic disease and its treatment. The purpose of this study was to examine illness intrusiveness and QOL in Epilepsy in patients with different levels of seizure control. METHODS: Cross-sectional data were obtained and compared between two groups of patients categorized by presence of seizures: seizure freedom or continued seizures (N = 145). Standard instruments measured the following variables: illness intrusiveness, perceived personal control, subjective well-being, and disease specific QOL. RESULTS: Illness intrusiveness varied inversely and significantly with seizure control. Complete seizure freedom, whether achieved by pharmacological or surgical treatment, was associated with the lowest levels of illness intrusiveness. Seizure freedom was also associated with increased perceived control, positive affect, self-esteem and QOL in Epilepsy. CONCLUSIONS: The most robust benefits of decreased illness intrusiveness in Epilepsy occur when treatment leads to c ...

Source: www.ncbi.nlm.nih.gov --- 4 days ago
Modeling Epilepsy with pluripotent human cells. Epilepsy Behav. 2008 Oct 6; Authors: Muotri AR Pluripotency is generally defined by the ability to differentiate into cell types representing all three germ layers: ectoderm, mesoderm, and endoderm. Human pluripotent stem cells hold great promise in regenerative medicine and in cell replacement therapies because of their ability to self-renew and their developmental potential to become all cell types in the body. Moreover, pluripotent cells represent a unique system in which to study the normal development of the human nervous system and the several instances where the process may fail. Here, I propose several strategies for how pluripotent stem cells, both human embryonic stem cells and induced pluripotent stem cells, can potentially be used to gain insights into the biology of temporal lobe Epilepsy. PMID: 18845273 [PubMed - as supplied by publisher] ...

Source: www.ncbi.nlm.nih.gov --- 8 days ago
Related Articles Immunology and Epilepsy. Rev Neurol Dis. 2008;5(3):109-16 Authors: Najjar S, Bernbaum M, Lai G, Devinsky O Immune mechanisms play a critical role in systemic disorders (systemic lupus erythematosus, Sjögren's syndrome, Crohn's disease, and sarcoidosis) and in localized central nervous system (CNS) disorders (CNS vasculitis, multiple sclerosis, acute disseminated encephalomyelitis, and encephalitides). Both humoral and cell-mediated mechanisms are involved in the systemic and CNS-limited disorders. Immune mechanisms may also be a factor in a number of epilepsies such as Rasmussen's encephalitis, Lennox-Gastaut syndrome, Landau-Kleffner syndrome, and temporal lobe Epilepsy. Immunologic abnormalities are found in routine Epilepsy surgical specimens, suggesting a broader role of immunopathology in the etiology of Epilepsy. The prevalence and impact of immunopathology in Epilepsy syndromes remains to be determined by future research. PMID: 18838950 [PubMed - in process] ...

Source: www.ncbi.nlm.nih.gov --- 1 day ago
Related Articles Levetiracetam-induced depression in a 5-year-old child with partial Epilepsy. Seizure. 2008 Oct 8; Authors: Tamarelle C, Pandit F, Mazarati A, Riquet A, Vallée L, Auvin S Depression in children and adolescents with Epilepsy is common. Depression worsen quality of life in Epilepsy patients. Neurobiological, social, and iatrogenic factors may play a role in depressive disorder development. We report a patient with partial Epilepsy secondary to neonatal stroke, who developed depressive disorder as a result of levetiracetam (LEV) treatment. Our report illustrates the possible implication of iatrogenic factors in depression among Epilepsy patients. However, recent data suggest that LEV may be effective in case of affective disorders. We discuss the factors linking Epilepsy with depression. Because of its high incidence and its multiple physiopathologic factors, psychiatric comorbidity should be always assessed in pediatric epileptic patients. PMID: 18848469 [PubMed - as supplied by publisher] ...

Source: www.ncbi.nlm.nih.gov --- 12 days ago
Related Articles Anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, in rat models of Epilepsy. Br J Pharmacol. 2008 Jul;154(5):1116-24 Authors: Zhao R, Zhang XY, Yang J, Weng CC, Jiang LL, Zhang JW, Shu XQ, Ji YH BACKGROUND AND PURPOSE: The sodium channel is a primary target for treating central nervous system disorders such as Epilepsy. In this study the anticonvulsant effect of BmK IT2, a sodium channel-specific neurotoxin, was evaluated in different animal models of Epilepsy. EXPERIMENTAL APPROACH: Experiments were performed on freely moving rats made epileptic by administration of either pentylenetetrazole (PTZ) or pilocarpine. BmK IT2 (0.05-0.5 microg in 2 microl) was microinjected into the CA1 area and its effects on PTZ-induced widespread, seizure-like behaviour and cortex epileptiform EEG, as well as on pilocarpine-induced seizure-like behaviour and c-Fos expression were studied. KEY RESULTS: Intrahippocampal application of BmK IT2 dose-dependently inhibited PTZ-induced seizure-like behaviour, and reduced the numbers and duration of the high amplitude and frequency discharges (HAFDs) of the epileptiform EEG component induced by PTZ. Similarly, in the pilocarpine-induced status epilepticus (SE) model, BmK IT2 significantly prolonged the latency to onset of the SE, reduced the severity of SE and suppressed hippocampal c-Fos expression during SE. CONCLUSIONS AND IMPLICATIONS: BmK IT2 showed anticonvulsant acti ...

Source: www.ncbi.nlm.nih.gov --- 2 days ago
Related Articles The combined burden of cognitive, executive function, and psychosocial problems in children with Epilepsy: a population-based study. Dev Med Child Neurol. 2008 Jul;50(7):530-6 Authors: Høie B, Sommerfelt K, Waaler PE, Alsaker FD, Skeidsvoll H, Mykletun A The combined burden of psychosocial (Achenbach scales), cognitive (Raven matrices), and executive function (EF) problems was studied in a population-based sample of 6- to 12-year-old children with Epilepsy (n=162; 99 males, 63 females) and in an age- and sex-matched control group (n=107; 62 males, 45 females). Approximately 35% of the children with Epilepsy had severe non-verbal cognitive problems. In those that did not, mild cognitive problems (26% vs 11%, p=0.005), EF problems (31% vs 11%, p<0.001), and psychosocial problems (45% vs 10%, p<0.001) were each much more common than among controls. Having problems in two or all three of these areas simultaneously was more frequent among the children with Epilepsy (14% vs. 3%, p<0.001 and 4% vs 0%, p<0.001 respectively). Excluding those having remote symptomatic Epilepsy aetiology did not change the problem load significantly for the children with Epilepsy with the important exception that having severe non-verbal problems was approximately halved from 35 to 18%. In 30 children with benign Epilepsy of childhood with centrotemporal spikes, mild cognitive problems were somewhat more common, but psychosocial and EF problems ...

Source: www.medicinenet.com --- 2 days ago
Title: Health Tip: Coping With Epilepsy Category: Health News Created: 10/11/2008 2:00:00 AM Last Editorial Review: 10/13/2008 ...

Source: stlouis.bizjournals.com --- 14 days ago
The St. Louis Rams fired an assistant trainer because he has Epilepsy, alleges a lawsuit the U.S. Equal Employment Opportunity Commission filed this week. ...

Source: www.medicalnewstoday.com --- 15 days ago
The International Bureau for Epilepsy (IBE) in partnership with UCB, launched a new Journalism Award. The 'Excellence in Epilepsy' Journalism Award invites journalists from around the world to submit stimulating, informed and compelling news and feature stories on Epilepsy. The Award is part of a global initiative to increase awareness and understanding of a condition that affects 50 million people, but still remains widely misunderstood. ...

Source: www.medicalnewstoday.com --- 15 days ago
Novel Treatment Also Demonstrated Significant Improvement in Quality of Life and Reduction in Depressive Symptoms Positive data from three phase III studies presented at the 8th European Congress of Epileptology, Berlin, Germany, demonstrated that Zebinix(TM) (1) ...

Source: www.medicalnewstoday.com --- 2 days ago
Vimpat (lacosamide), a new adjunctive therapy in the treatment of partial-onset seizures with or without secondary generalisation in patients with Epilepsy aged 16 years and older, has been launched in the UK. ...

Source: www.moreover.com --- 3 days ago
Yomiuri Shimbun Oct 12 2008 6:54PM GMT ...

Source: healthnews.uc.edu --- 21 hours ago
Jon Zipperstein, Susan Muth and Michael Privitera, MD, will host “Innovations in Epilepsy Research” from 6 to 8:30 p.m. Sunday, Oct. 26, at Embers Restaurant in Madeira. The second annual event will raise funds for Epilepsy research at the Epilepsy Center at the University of Cincinnati Neuroscience Institute. ...

Source: vocuspr.vocus.com --- 2 days ago
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Source: kdka.com --- 5 days ago
Jessica Wilson, 15, has a lot to look forward to. "Driving is coming up in the next couple years," she says. Just a year ago, driving wasn't a realistic goal for Jessica. She's had Epilepsy since she was six, and her seizures were unpredictable. ...

Source: totalplaystation.com --- 8 days ago
WipEout HD is everything you imagined it would be. ...

Source: www.maidenhead-advertiser.co.uk --- 6 days ago
A nine-year-old girl found dead in bed by her father died of natural causes, an inquest has heard.An inquest at the Guildhall in Windsor today heard how Chloe Davis was discovered ...