Decay

Source: www.ncbi.nlm.nih.gov --- 10 days ago
Related Articles Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I Decay rates. J Immunol. 2008 Oct 15;181(8):5199-203 Authors: Rudd BD, Brien JD, Davenport MP, Nikolich-Zugich J TLR ligands are among the key stimuli driving the optimal dendritic cell (DC) maturation critical for strong and efficacious T cell priming. In this study, we show that part of this effect occurs via increased TCR triggering. Pretreatment of DCs with TLR ligands resulted in the triggering of many more TCRs in responding CD8(+) T cells. Importantly, even when DCs expressed the same amount of cognate peptide-MHC (pMHC) molecules, TLR ligand treatment resulted in down-regulation of larger numbers of TCR molecules. This was independent of the up-regulation of costimulatory, adhesion or cytokine molecules or the amount of noncognate pMHCs. Rather, DCs pretreated with TLR ligands exhibited increased stability of cognate pMHCs, enabling extended TCR triggering. These findings are of potential importance to T cell vaccination. PMID: 18832671 [PubMed - in process] ...

Source: www.ncbi.nlm.nih.gov --- 3 days ago
The effect of experimental parameters on the signal Decay in double-PGSE experiments: Negative diffractions and enhancement of structural information. J Magn Reson. 2008 Sep 17; Authors: Shemesh N, Cohen Y Double pulsed gradient spin echo (d-PGSE) experiment has been recently suggested for detecting microscopic anisotropy in macroscopically isotropic samples. This sequence is complex and has many variables, including, intra alia, combinations of directions and amplitudes of the pulsed gradients, diffusion times in each of the encoding periods and the mixing time period. The effect of these experimental parameters of the d-PGSE sequence was studied in an array of water filled microcapillaries of micron diameters. We found that negative diffractions occur, as indeed predicted by recently published simulations. We also found differential effects of prolongation of the mixing time between collinear and orthogonal d-PGSE experiments. The d-PGSE experiment in the collinear direction perpendicular to the long axis of the cylinder exhibited a marked dependence on the mixing time, while the orthogonal d-PGSE experiment exhibited no such dependence at all. Interestingly, one of the most important predictions by the simulations was that the d-PGSE sequence could potentially discriminate between compartments of different sizes better than the single PGSE (s-PGSE) and it seems that our experimental results indeed corroborate these predictions. PM ...

Source: www.ncbi.nlm.nih.gov --- 3 days ago
Mitochondrial Decay in the Brains of Old Rats: Ameliorating Effect of Alpha-Lipoic Acid and Acetyl-L: -carnitine. Neurochem Res. 2008 Oct 10; Authors: Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J To investigate the mitochondrial Decay and oxidative damage resulting from aging, the activities/kinetics of the mitochondrial complexes were examined in the brains of young and old rats as well as in old rats fed R-alpha-lipoic acid plus acetyl-L: -carnitine (LA/ALC). The brain mitochondria of old rats, compared with young rats, had significantly decreased endogenous antioxidants and superoxide dismutase activity; more oxidative damage to lipids and proteins; and decreased activities of complex I, IV and V. Complex I showed a decrease in binding affinity (increase in K(m)) for substrates. Feeding LA/ALC to old rats partially restored age-associated mitochondrial dysfunction to the levels of the young rats. These results indicate that oxidative mitochondrial Decay plays an important role in brain aging and that a combination of nutrients targeting mitochondria, such as LA/ALC, could ameliorate mitochondrial Decay through preventing mitochondrial oxidative damage. PMID: 18846423 [PubMed - as supplied by publisher] ...

Source: www.prnewswire.com --- 2 minutes ago
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Source: www.springerlink.com --- 5 days ago
Abstract   We study the Decay and smoothness of solutions of the dispersion managed non-linear Schrödinger equation in the case of zero residual dispersion. Using new x -space versions of bilinear Strichartz estimates, we show that the solutions are not only smooth, but also fast decaying. Content Type Journal Article DOI 10.1007/s00220-008-0612-4 Authors Dirk Hundertmark, University of Birmingham School of Mathematics, Watson Building Edgbaston, Birmingham B15 2TT UK Young-Ran Lee, Sogang University Department of Mathematics Shinsu-dong 1 Mapo-gu, Seoul 121-742 South Korea Journal Communications in Mathematical Physics Online ISSN 1432-0916 Print ISSN 0010-3616 ...

Source: www.medicalnewstoday.com --- 7 days ago
Children covered under Medicaid receive considerably less dental care and have more untreated tooth Decay than those who are privately insured, witnesses testified during a recent hearing held by the House Oversight and Government Reform Domestic Policy Subcommittee, CQ HealthBeat reports. According to CQ HealthBeat, a ...

Source: prd.aps.org --- 1 hour ago
Author(s): D. T. da Silva, M. L. da Silva, J. N. de Quadros, and D. Hadjimichef The ^{3} P _{0} model, in which qq [over ¯] pair production is the dominant mechanism, is extensively applied to both light and heavy meson Decay and stands as one of the most successful strong Decay models. The pair production can be obtained from the nonrelativistic limit of a microscopic interac... [Phys. Rev. D 78, 076004] Published Wed Oct 15, 2008 ...

Source: prl.aps.org --- 7 days ago
Recent experimental data at GSI on the rates of the number of daughter ions, produced by the nuclear K-shell electron capture (EC) decays of the H-like ions 140Pr58+ and 142Pm60+, suggest that they are modulated in time with periods TEC @ 7 sec and amplitudes aEC @ 0.20. Since it is known that ... ...

Source: www.physicsforums.com --- 6 days ago
*1. The problem statement, all variables and given/known data* Q(t) is the amount of carbon 14 at time t. Given half life of 5730 years, and assuming that Q satisfies dQ/dt=-rQ; determine Decay... ...

Source: www.stylehive.com --- 10 days ago
TouchyCooL saved 24 months ago at 04:06 AM PDT on Oct 6, 2006 Description: Not anything but i like::: see more details   ...

Source: www.physicsforums.com --- 10 days ago
*1. The problem statement, all variables and given/known data* hello everybody I am new too these forums and am looking for a little help on a problem. I don't want anyone to give me the answer so i... ...

Source: stacks.iop.org --- 6 hours ago
Author(s): M Genkin and E Lindroth Affiliation(s): Atomic Physics, University of Stockholm, Sweden ...

Source: stacks.iop.org --- 3 days ago
Author(s): K Enqvist, S Nurmi and G I Rigopoulos Affiliation(s): Department of Physics, University of Helsinki, PO Box 64, FIN-00014, Finland; Helsinki Institute of Physics, University of Helsinki, PO Box 64, FIN-00014, Finland ...

Source: www.marginalrevolution.com --- 41 days ago
Robert Gibbons wrote: When I first read Coase’s (1984: 230) description of the collected works of the old-school institutionalists – as “a mass of descriptive material waiting for a theory, or a fire” – I thought it was (a) hysterically... ...

Source: bostonist.com --- 7 days ago
The Commonwealth of Massachusetts is on the verge of fiscal crisis . Standard & Poor's certifies that the state has enough cash to make it through the end of the year. After that, it's a toss-up. Revenue for the first quarter of fiscal year 2009 is down $233 million, and many believe that the state will have to slash $1 billion from next year's budget. The culprit? Capital gains tax shortfalls, according to one e-pundit. Are the people of Massachusetts stupid enough to make a bad situation worse by voting away the state income tax? Probably not , says Edward L. Glaeser, a Harvard professor. (Shout-out to UHub .) ...

Source: www.optionetics.com --- 13 days ago
Options expire after a certain period of time, so you need to understand time value and intrinsic value as they pertain to option trading. ...