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Source: www.moreover.com --- 6 days ago
A scientist testifying for the state told a jury Monday that DNA taken from two rape victims matched a sample from Joshua Lamar Smith. Smith, 18, of St. Paul, is on trial in Ramsey County District Court on two counts of criminal sexual conduct. ... Source: www.odt.co.nz --- 8 days ago
Identification is at the centre of the trial of Liam James Reid, charged with the rape and murder of Emma Agnew in Christchurch and the rape and attempted murder of a woman in Dunedin nine days later, a court was told today. read more ... Source: www.fox17.com --- 3 days ago
KNOXVILLE, Tenn. (AP) -- Prosecutors in Knoxville say DNA testing links an illegal immigrant to the rape and slaying of a former Alabama homecoming queen. ... Source: www.nbc-2.com --- 2 days ago
The fifth day of testimony in the murder trial of Fred Cooper focused on the DNA found at the scene where Michelle and Steven Andrews were murdered in December 2005. ... Source: www.denverpost.com --- 6 days ago
A person already charged as a "John Doe" based on DNA Evidence in a series of car break-ins and thefts has been identified, arrested and jailed. ... Source: www.topix.com --- 4 days ago
A Penfield prison parolee was convicted Monday of killing a Rochester woman 15 years ago. ... Source: www.ncbi.nlm.nih.gov --- 4 days ago
Related Articles Noninvasive diagnosis of fetal aneuploidy by shotgun sequencing DNA from maternal blood. Proc Natl Acad Sci U S A. 2008 Oct 6; Authors: Fan HC, Blumenfeld YJ, Chitkara U, Hudgins L, Quake SR We directly sequenced cell-free DNA with high-throughput shotgun sequencing technology from plasma of pregnant women, obtaining, on average, 5 million sequence tags per patient sample. This enabled us to measure the over- and underrepresentation of chromosomes from an aneuploid fetus. The sequencing approach is polymorphism-independent and therefore universally applicable for the noninvasive detection of fetal aneuploidy. Using this method, we successfully identified all nine cases of trisomy 21 (Down syndrome), two cases of trisomy 18 (Edward syndrome), and one case of trisomy 13 (Patau syndrome) in a cohort of 18 normal and aneuploid pregnancies; trisomy was detected at gestational ages as early as the 14th week. Direct sequencing also allowed us to study the characteristics of cell-free plasma DNA, and we found Evidence that this DNA is enriched for sequences from nucleosomes. PMID: 18838674 [PubMed - as supplied by publisher] ... Source: www.ncbi.nlm.nih.gov --- 5 days ago
Related Articles The potential of PARP inhibitors in genetic breast and ovarian cancers. Ann N Y Acad Sci. 2008 Sep;1138:136-45 Authors: Drew Y, Calvert H The abundant nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1), represents an important novel target in cancer therapy. PARP-1 is essential to the repair of DNA single-strand breaks via the base excision repair pathway. Inhibitors of PARP-1 have been shown to enhance the cytotoxic effects of ionizing radiation and DNA damaging chemotherapy agents, such as the methylating agents and topoisomerase I inhibitors. There are currently at least five PARP inhibitors in clinical trial development. Recent in vitro and in vivo Evidence suggests that PARP inhibitors could be used not only as chemo/radiotherapy sensitizers, but as single agents to selectively kill cancers defective in DNA repair, specifically cancers with mutations in the breast cancer associated (BRCA) 1 and 2 genes. This theory of selectively exploiting cells defective in one DNA repair pathway by inhibiting another is a major breakthrough in the treatment of cancer. BRCA1/2 mutations are responsible for the majority of genetic breast/ovarian cancers, known as the hereditary breast ovarian cancer syndrome. This review summarizes the preclinical and clinical Evidence for the potential of PARP inhibitors in genetic breast and ovarian cancers. PMID: 18837894 [PubMed - in process] ... Source: www.ncbi.nlm.nih.gov --- 5 days ago
Related Articles Reduced expression of SRC family kinases decreases PI3K activity in NBS1(-/-) lymphoblasts. Biochem Biophys Res Commun. 2008 Sep 30; Authors: Sagan D, Eckardt-Schupp F, Eichholtz-Wirth H SRC family kinases (SFKs) are involved in the activation of phosphatidylinositol-3-kinase (PI3K). In addition, the activity of this lipid kinase can be regulated by the DNA repair protein NBS1. Here, we describe a disturbed expression of some members of the non-receptor tyrosine kinase family in lymphoblastoid cell lines generated from cells of Nijmegen breakage syndrome (NBS) patients. Especially, only minor amounts of the kinases LCK and HCK are expressed in the NBS1(-/-) cell lines as compared to the consanguineous NBS1(+/-) cells. We demonstrate that SFK activity is important for a proper activation of PI3K in these cells and that it is reduced in NBS1(-/-) cells. We provide Evidence that the observed reduced PI3K activity in NBS lymphoblasts is caused by an impaired expression of the SFKs LCK and/or HCK. Thus, our data establish a new function for the NBS1 protein as a regulator of PI3K activity via SFK members. PMID: 18835245 [PubMed - as supplied by publisher] ...
Source: www.reason.com --- 21 hours ago
Kennedy Brewer is one of two men thus far shown to have been wrongly convicted based on the testimony of the now former Mississippi medical examiner Dr. Steven Hayne and disgraced forensic odontologist Dr. Michael West. Brewer filed suit against the two last week. Brewer is asking for $18 million, plus unspecified punitive damages. As an aside, it’s really too bad that it’s so incredibly difficult to sue prosecutors , because Mississippi District Attorney Forrest Allgood should really be included in this suit. Even assuming Allgood wasn’t aware of Hayne’s and West’s dishonesty at the time of the trial (and there’s plenty of reason to think he was fully aware of it), it was Allgood’s efforts to protect his conviction , his continued reliance on West’s testimony as the chief Evidence against Brewer in the appeals process long after West had been exposed as a fraud, and his stubborn refusal to check the DNA in the case against the state’s database that kept Kennedy Brewer in prison years after DNA tests exonerated him. Allgood’s obstinance in the Brewer case also prolonged the wrongful imprisonment of another man, Levon Brooks. When the DNA samples were finally run against the state database, they pointed to a single man as the culprit in the separate crimes for which Allgood convicted Brooks and Brewer. He later confessed. My sources say part of the reason Allgood was so stubborn in the Brewer case is that he knew DNA testin ... Source: www.thedenverchannel.com --- 5 days ago
Denver police are now using DNA Evidence in helping to solve burglaries. ... Source: www.kentucky.com --- 6 days ago
A death row inmate has asked a judge to overturn his murder conviction and sentence because DNA tests showed more than one person's genetic material on Evidence from the case. Attorneys for Brian Keith Moore said the presence of DNA from more than one person on a shirt and jacket contradicts the prosecution's argument that Moore was alone when he killed Virgil Harris in Louisville in August 1979. The attorneys filed the motion Tuesday asking that the sentence and conviction be set aside, less than a week after Jefferson Circuit Judge James Shake declined to order more specific DNA tests on the Evidence. "This court has found that the Evidence of Moore's guilt is equally consistent with his innocence," attorney David Barron wrote. "And, DNA results show that someone else's DNA is on the clothing worn by the killer when the murder was committed." Allison Martin, a spokeswoman for the Kentucky Attorney General's Office, said prosecutors will be filing a response to the motion, but declined comment on its merits. ... Source: www.kentucky.com --- 5 days ago
As DNA testing reveals the unreliability of traditional lineups, Lexington police still use a method that produces even more false identifications. On Sunday, Herald-Leader staffers Delano R. Massey and Valarie Honeycutt Spears told the story of Corey Jackson, a young black man who is in prison because the white victim of an armed robbery identified him as he was handcuffed and surrounded by white officers near the scene of the crime. There were no other eyewitnesses or physical Evidence. Police never recovered the assailant's gun or the victim's purse or its contents, even though Jackson was picked up less than a half-hour after the robbery. The only money in the purse was a $5 bill; Jackson was carrying one $20 bill. He said he was going to change it for bus fare to go take his General Educational Development test. A jury of 10 white women, one white man and one black man convicted him, and he was sentenced to 13 years. ... Source: www.roanoke.com --- 7 days ago
A Roanoke grand jury has returned indictments in two unsolved killings and a rape from the mid-1980s that have been linked to the same suspect by DNA Evidence. ... Source: www.daytondailynews.com --- 5 days ago
Darke County officials hope the public and DNA Evidence will help them solve a homicide case 38 years after a female's nude, decomposing body was found in a cornfield. ... Source: www.roanoke.com --- 5 days ago
"There hopefully will be additional Evidence to supplement the DNA," the prosecutor said. When Roanoke police sent samples taken from the Cynthia McCray and Audrey West homicide cases to the state forensic lab more than 20 years ago, scientists could do little more than identify blood types and keep Evidence for comparison if investigators ever found a suspect. ...
Source: www.bignewsnetwork.com --- 7 days ago
ROANOKE, Va. (AP) - Roanoke's chief prosecutor says DNA Evidence has linked a prison inmate to two unsolved slayings and a rape from the 1980s. Commonwealth's Attorney Donald Caldwell says recent DNA... ... Source: www.marshallparthenon.com --- 6 days ago
Analysts at the mitochondrial DNA laboratory in Phoenix, Ariz., are testing crime scene Evidence from the disappearance and death of Marshall student Leah Hickman in hopes of linking suspects to the incident. Huntington Police Sgt. John Williams, lead investigator for the case, said he could not disclose what Evidence was being tested, but common trace Evidence includes things such as fibers and hair. ... Find more results for DNA Evidence on RSSMicro.com |
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