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Source: www.nytimes.com --- 12 hours ago
A construction boom tied to the Olympics is threatening two types of housing in China’s capital. ... Source: www.ncbi.nlm.nih.gov --- 13 hours ago
Related Articles Nuclear Architecture and chromatin dynamics revealed by atomic force microscopy in combination with biochemistry and cell biology. Pflugers Arch. 2008 Apr;456(1):139-53 Authors: Hirano Y, Takahashi H, Kumeta M, Hizume K, Hirai Y, Otsuka S, Yoshimura SH, Takeyasu K The recent technical development of atomic force microscopy (AFM) has made nano-biology of the nucleus an attractive and promising field. In this paper, we will review our current understanding of nuclear Architecture and dynamics from the structural point of view. Especially, special emphases will be given to: (1) How to approach the nuclear architectures by means of new techniques using AFM, (2) the importance of the physical property of DNA in the construction of the higher-order structures, (3) the significance and implication of the linker and core histones and the nuclear matrix/scaffold proteins for the chromatin dynamics, (4) the nuclear proteins that contribute to the formation of the inner nuclear Architecture. Spatio-temporal analyses using AFM, in combination with biochemical and cell biological approaches, will play important roles in the nano-biology of the nucleus, as most of nuclear structures and events occur in nanometer, piconewton and millisecond order. The new applications of AFM, such as recognition imaging, fast-scanning imaging, and a variety of modified cantilevers, are expected to be powerful techniques to reveal the nanostructure o ... Source: www.ncbi.nlm.nih.gov --- 13 hours ago
Related Articles Architecture of the SWI/SNF-Nucleosome Complex. Mol Cell Biol. 2008 Jul 21; Authors: Dechassa ML, Zhang B, Horowitz-Scherer R, Persinger J, Woodcock CL, Peterson CL, Bartholomew B The SWI/SNF complex disrupts and mobilizes chromatin in an ATP-dependent manner. SWI/SNF interactions with nucleosomes were mapped by DNA footprinting, site-directed DNA and protein cross-linking when SWI/SNF was recruited by a transcription activator. SWI/SNF was found by DNA footprinting to contact tightly about one gyre of DNA spanning approximately 50 bps from the nucleosomal entry site to near the dyad axis. The DNA footprint is consistent with nucleosomes binding to an asymmetric trough of SWI/SNF that was revealed by improved imaging of free SWI/SNF. The DNA site-directed cross-linking revealed that the catalytic subunit Swi2/Snf2 is associated with nucleosomes two helical turns from the dyad axis and the Snf6 subunit is proximal to the transcription factor recruiting SWI/SNF. The highly conserved Snf5 subunit associates with the histone octamer and not with nucleosomal DNA. The model of the binding trough of SWI/SNF illustrates how nucleosomal DNA can be mobilized while SWI/SNF remains bound. PMID: 18644858 [PubMed - as supplied by publisher] ... Source: www.washingtonpost.com --- 12 hours ago
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Source: www.upenn.edu --- 15 hours ago
Unique and visually playful exhibit exploring the spaces in which we read, and how those spaces influence what we read-- showcasing a broad range of items from Penn's Rare Book and Manuscript Library. ... Source: www.computerworld.com --- 23 hours ago
(Source: Oracle) Oracle Database 11g for Windows provides an optimized database solution for deployments that require enterprise scalability, reliability, and high performance. Learn more about the Architecture of Oracle database on Windows and how it differs from its counterparts on UNIX and Linux, in this new whitepaper. ... Source: www.post-gazette.com --- 7 hours ago
TULSA, Okla. -- Think Art Deco Architecture, and what places pop into your head? New York. Miami Beach. Los Angeles. Tulsa. ... ... Source: jobs.joelonsoftware.com --- 18 hours ago
Draper Laboratory is an independent, not-for-profit engineering research and development organization. Its mission is to serve the national interest in applied research, engineering development, education and technology transfer. The core competencies leveraged in Draper's work are guidance, navigation and control for strategic systems; precision targeting and information management and decision systems; autonomous air, land, sea and space systems; reliable, fault-tolerant embedded software; and miniature, low-power electronic and mechanical systems. We are located in Cambridge, Ma. The candidate will be responsible for the design and development of large software-based enterprise architectures to support the deployment of next generation Net-Centric Intelligence, Surveillance and Reconnaissance ground systems for the DoD. Candidates from the travel or financial industry are encouraged to apply. M.S. in Computer Science, Computer Engineering, Systems Engineering, Aerospace Engineering or equivalent is required with eight years plus experience. Applicants must be able to demonstrate their background in building enterprise systems. You should be familiar with Service-oriented Architecture, Websphere, Plumtree, Java Enterprise System and Web 2.0. Relocation assistance is available. Applicants selected will be subject to a government security investigation and must meet eligibility requirements for access to classified information. To app ... Source: www.channelnewsasia.com --- 20 hours ago
SINGAPORE : Singapore's Foreign Minister George Yeo on Wednesday said that ties between ASEAN and the United States will remain a key pillar in the evolving political and security Architecture of the region. ... Source: www.forrester.com --- 10 hours ago
... Source: pecus.jaiku.com --- 2 hours ago
Nov 24, 2008: MAKE ART 2008 - OpenOS at Maison de l'Architecture Fetched from Upcoming.org Combined Feed 1 day, 14 hours ago. ...
Source: archrecord.construction.com --- 1 hour ago
... Source: www.it-analysis.com --- 35 minutes ago
By: Neil Ward-Dutton , Research Director , Macehiter Ward-Dutton Posted: 23rd July 2008 This work is licensed under a Creative Commons License Via Service Oriented Enterprise , I recently picked up an Infoworld blog post by SOA journeyman David Linthicum, where he makes a couple of very strange points about SOA and ESBs. It may be, of course, that the post is pure link bait : certainly, David appears to have said some relatively sane things in the past, so that might be it. If it is link bait, I'm going to fall for it now. In his piece David quotes a representative from iTKO , who repeats the now well-understood insight that in some large organisations, there's a challenge that arises because different groups with SOA initiatives find themselves having to integrate different ESBs in order to pull together implementations for cross-silo scenarios. He then goes on to comment (I?ve taken the liberty of extracting elements of his piece below): First, if there is indeed 'enterprise Architecture' and an 'enterprise architect' then the different divisions should not be using different ESBs, or even an ESB for that matter... Second, considering that my first point is correct (which it is), why the heck are you attempting to integrate these integration engines when they should perhaps be displaced altogether. Because, call me crazy again, that would be cheaper... just to be clear, you determine your requirements, and then the solutions pat ... Source: archinect.com --- 4 hours ago
While a dark flood of pseudo-critical article's on Beijing's urban transformation is clogging the international press channels, few have focused on stadia other than the Cube or the Nest. Bert de Muynck | movingcities published in a recent issue of MARK Magazine 'Olympic Architecture' highlighting the background of the basket stadium, velodrome, tennis stadia,... and others while checking their impact on the urban development of Beijing. ... Source: home.wickedlocal.com --- 21 hours ago
An old shingled building at the oceanside end of S Street, once part of Hull’s hotel heyday of the early 20th century, will be replaced — ironically by some Architecture that will evoke that era. A large home for new owners is being designed by Hull architect Don Ritz to recall the Shingle Style Victorian-era Architecture [...] ... Source: www.citeulike.org --- 10 hours ago
icse, Vol. 0 (2004), pp. 533-542. ... Source: www.directionsmag.com --- 6 hours ago
Author Dave Peters Shares a Sound Methodology for Infrastructure Planning Redlands, California— Launching a geographic information system (GIS) involves more than investing in GIS software and a bank of computers. Organizations must first design the system infrastructure, a process succinctly spelled out in ... Source: artcompetitionslist.blogspot.com --- 19 hours ago
The International Archive of Women in Architecture (IAWA) center, in Virginia Tech’s College of Architecture and Urban Studies, invites architects, scholars, and researchers to honor IAWA founder and Virginia Tech emerita faculty member Milka Bliznakov through their research on women in Architecture and related design fields. This research, in concert with the preservation efforts of the IAWA, ... Find more results for Architecture on RSSMicro.com |
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Manageability & Automation - It is all about planning!!! How can Architecture help: The primary role of Architecture is to provide an orchestrated plan to meet short term and long term Manageability & Automation (M&A) objectives. Architecture is all about technical planning and can enable reduced operational costs and agility if done correctly. I strongly believe that Architecture can help accelerate the rate of change and provide real value for "M" and for "A". Some specific Architecture-enabling activities include: Service Definition - Define the core Services and what are in/out Scope . Example below. Taxonomy - Define the next level of Services details. Example below. Establish a high-level Strategy and Conceptual Architecture (5-10 year vision). Example below. Define a strategy with a set of guiding principles / policies to enable the M&A. These may include: Vendor strategy (single / multiple sourcing) Integration "Frameworks and/or Point Solutions" (or combo) strategy Operation model strategy (centralized / distributed) Data strategy Define a 3-year horizon "capabilities" roadmap with the first year committed (partnership of Architecture, Operations and Engineering) and the last two years a best guess based on realistic funding, estimated vendor product delivery schedules, business trends, emerging / disruptive technologies, etc. Use this roadmap to communicate and synchronize with vendor roadmaps, driving your requirements into ...
Intel has just announced a System on Chip (SoC) product named EP80579. The basic idea of a SoC is to integrate as many components of a computer as possible in a chip. That allows to reduce the size, cost and power consumption… Right now, these Intel chips are often used to power devices such as network attached storages and so on... The more interesting part of Intel’s announcement is that upcoming SoC will use the Atom processor design and will have higher performance. Atom is used today to power Mobile Internet Devices (MID) and NetTop computers. In the near future, this entry into the SoC segment might translate into faster time-to-market for new designs and a larger software applications offering. Source article | Add a comment ...