Antidepressant

Source: mentalhealth.about.com --- 25 days ago
September 2000 study finds that exercise also keeps depression from returning. ...

Source: topics.nytimes.com --- 34 days ago
Drug regulators recommended against the use of antidepressants in the treatment of depressed children under 18. ...

Source: mentalhealth.about.com --- 23 days ago
Antidepressant medications are one of the most important treatments for depression. Along with psychotherapy, these medications can be lifesaving, and they improve the quality of life for millions. ...

Source: topics.nytimes.com --- 34 days ago
Forest Laboratories and H Lundbeck AS win Food and Drug Administration approval for Antidepressant Lexapro, successor to their drug Celexa; Forest licenses rights to both drugs in US from Lundbeck of Denmark, and says Lexapro will be available in US by Sept 5 ...

Source: www.ncbi.nlm.nih.gov --- 35 days ago
Related Articles Antidepressant prescribing and rapid cycling. Am J Psychiatry. 2008 Aug;165(8):1048-9; author reply 1049 Authors: Goldberg J PMID: 18676603 [PubMed - indexed for MEDLINE] ...

Source: www.ncbi.nlm.nih.gov --- 38 days ago
Related Articles [Treatment of chronic back pain with Antidepressant cymbalta: an experimental study] Zh Nevrol Psikhiatr Im S S Korsakova. 2007;107(7):20-4 Authors: Voznesenskaia TG, Leonova AR, Kaverina IV Thirty-two patients at the acute stage of chronic back pain have been studied. Cymbalta was used as a monotherapy in dosage 60 mg daily during 6 weeks simultaneously with traditional non-pharmacological therapy. Treatment efficacy was assessed using self-rating methods and quantitative scales measuring pain intensity as well as Spilberger trait/state anxiety inventory, Beck depression scale, Plutchik scale measuring psychological defense mechanisms, quality of sleep, quality of life and evaluation of autonomic dysfunction. The treatment with cymbalta resulted in significant reduction of pain in 90% patients, with full stopping of the syndrome in 10% and marked reduction in 55%. The stopping of pain syndrome was correlated with significant improvement of emotional status and quality of life and sleep normalization of the patients. PMID: 18379477 [PubMed - indexed for MEDLINE] ...

Source: www.ncbi.nlm.nih.gov --- 28 days ago
Related Articles A double-blind comparison of sexual functioning, Antidepressant efficacy, and tolerability between agomelatine and venlafaxine XR. J Clin Psychopharmacol. 2008 Jun;28(3):329-33 Authors: Kennedy SH, Rizvi S, Fulton K, Rasmussen J Impaired sexual function is associated with major depressive disorder in the untreated state and is often more prevalent during Antidepressant therapy, which frequently results in poor treatment compliance. In this double-blind, multicenter study, the effects of agomelatine (an MT1 and MT2 agonist and 5HT-2C antagonist) and venlafaxine XR on sexual function were compared using the Sex Effects Scale in depressed patients. A total of 276 male and female patients received either agomelatine (50 mg) or venlafaxine XR (titrated to a target dose of 150 mg/d) for 12 weeks. Those who were sexually active at baseline (n = 193) and those who, in addition, achieved remission (n = 111) were defined a priori for analyses of change in sexual function. Treatment-emergent sexual dysfunction was significantly less prevalent among patients who received agomelatine, and venlafaxine XR was associated with significantly greater deterioration on the Sex Effects Scale domains of desire and orgasm. Both treatments resulted in equivalently high rates of remission (agomelatine, 73%; venlafaxine XR, 66.9%), although fewer patients in the agomelatine group discontinued treatment because of adverse events (agomelatine, 2.2 ...

Source: www.ncbi.nlm.nih.gov --- 28 days ago
Related Articles Antidepressant drugs and cardiovascular pathology: a clinical overview of effectiveness and safety. Acta Psychiatr Scand. 2008 Sep 8; Authors: Taylor D Objective: To review data examining the relationships between depression, antidepressants and cardiovascular disease. Method: Structured searches of PubMed, Medline and Embase conducted in March 2008. Results: Depression and cardiovascular disease are closely associated clinical entities. Depression appears both to cause and worsen cardiovascular disease. Cardiovascular disease is in turn associated with a high incidence of depression. Depression is associated with increased mortality in cardiovascular disease, and after myocardial infarction (MI) and stroke. Many antidepressants have cardiotoxic properties. Tricyclic drugs are highly cardiotoxic in overdose and may induce cardiovascular disease and worsen outcome in established cardiovascular disease. Reboxetine, duloxetine and venlafaxine are known to increase blood pressure. Other antidepressants have neutral or beneficial effects in various cardiovascular disorders. Conclusion: Sertraline, fluoxetine, citalopram, bupropion and mirtazapine appear to be safe to use after MI; the use of sertraline, and response to citalopram and mirtazapine may improve mortality. Paroxetine and citalopram appear to be safe to use in patients with established coronary artery disease. Limited data suggest that a variety of Antidepressant ...

Source: www.moreover.com --- 33 days ago
-- Use of Antidepressant medications is common among individuals who do not have any identifiable Axis I psychiatric disorders, according to results of a study presented here at the 58 Annual Conference of the Canadian Psychiatric Association (CPA). ...

Source: www.ncbi.nlm.nih.gov --- 7 days ago
Related Articles The relationship between Antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder. Curr Med Res Opin. 2008 Sep 30; Authors: Fishbain DA, Detke MJ, Wernicke J, Chappell AS, Kajdasz DK OBJECTIVE: Debate continues regarding whether onset of analgesia is faster than Antidepressant effect in antidepressants with both properties. Duloxetine hydrochloride (from here on referred to as duloxetine) is effective in both major depressive disorder and diabetic peripheral neuropathic pain. This post-hoc analysis of six placebo-controlled duloxetine trials in patients with major depressive disorder was designed to compare onset of Antidepressant activity to pain relief.RESEARCH DESIGN AND METHODS: Duloxetine was administered at 40-120 mg/day versus placebo for up to 9 weeks in outpatient clinic settings. The primary depression measure was the HAMD(17) and pain severity was measured using visual analog scale (VAS) measuring overall pain, headache, back and shoulder pain, and pain while awake. The time course of improvement was profiled using repeated measures modeling and Kaplan-Meier product limit estimation. RESULTS: In all but one case, significant reductions in HAMD(17) and VAS scores were seen within 2 weeks of treatment. Median time to VAS response was consistently shorter across all VAS measures than that to HAMD(17) respo ...

Source: www.ncbi.nlm.nih.gov --- 8 days ago
Related Articles HPA-axis regulation at in-patient admission is associated with Antidepressant therapy outcome in male but not in female depressed patients. Psychoneuroendocrinology. 2008 Sep 29; Authors: Binder EB, Künzel HE, Nickel T, Kern N, Pfennig A, Majer M, Uhr M, Ising M, Holsboer F A concatenation of data implicates a hyperactivity of the hypothalamus pituitary adrenal (HPA)-axis in the pathogenesis of depression and its normalization as a necessary predecessor of clinical response to Antidepressant drugs. In addition, regulation of the HPA-axis has been shown to be dependent on sex hormones. We therefore investigated gender differences in HPA-axis regulation in depression and its normalization during remission of clinical symptoms. We used the combined dexamethasone suppression/CRH stimulation (Dex-CRH) test to evaluate the degree of HPA-axis dysregulation in 194 in-patients with unipolar depression from the Munich Antidepressant Response Signature (MARS) study at both admission and discharge. The Hamilton Depression (HAM-D) Rating Scale was used to monitor clinical response to Antidepressant treatment. For both genders, we observed a normalization of HPA-axis dysregulation in remitters but not in non-remitters, both after 5 weeks of treatment and at discharge. The pattern of HPA-axis normalization with remission of depressive symptoms, however, showed gender-specific differences. In male patients, remission after 5 weeks of ...

Source: www.ncbi.nlm.nih.gov --- 6 days ago
Related Articles Guideline-consistent Antidepressant treatment patterns among veterans with diabetes and major depressive disorder. Psychiatr Serv. 2008 Oct;59(10):1139-47 Authors: Tiwari A, Rajan M, Miller D, Pogach L, Olfson M, Sambamoorthi U OBJECTIVE: This study estimated guideline-consistent Antidepressant treatment of depression among veterans with diabetes and examined its variation by patient-level demographic characteristics, socioeconomic characteristics, access to care, and health status. METHODS: Data were retrospectively analyzed from Veterans Health Administration (VHA) and Medicare claims of VHA clinic users with diabetes and major depressive disorder (N=3,953). Major depression was identified by using ICD-9-CM codes 296.2 and 296.3. Incident episode was identified by using 120-day negative diagnosis and medication history on or before the first depression diagnosis date in fiscal year 1999. Guideline-consistent depression treatment was defined as the receipt of antidepressants for at least 90 days within a period of six months after the onset of depression. Chi square tests and logistic regressions were used to analyze patterns of guideline-consistent Antidepressant treatment. RESULTS: Overall, 51% received any Antidepressant treatment for diagnosed major depression; among patients using any antidepressants, 62% received guideline-consistent Antidepressant treatment. VHA users who received care from a mental health spe ...

Source: www.nih.gov --- 8 days ago
In the new study at the National Institutes of Health in Bethesda, MD, depressed patients showed increasing activity in a mood-regulating hub near the front of the brain while viewing flashing frightful faces -- the more the increase, the better their response to an experimental fast-acting medication called ketamine. ...

Source: blogs.wsj.com --- 39 days ago
After years of declines, the rate of suicide among children and adolescents jumped sharply between 2003 and 2004. The rate fell slightly in 2005, but remained high enough to spur more debate about kids and antidepressants. ...

Source: www.ctv.ca --- 19 days ago
Labopharm Inc. has submitted a new drug application to the U.S. Food and Drug Administration for its once-daily formulation of Antidepressant trazodone which studies indicate reduces side-effects. ...

Source: www.mayoclinic.com --- 29 days ago
Antidepressant withdrawal is possible if you stop taking antidepressants abruptly — but it's generally preventable. Sponsored by: Chemotherapy.com - http://www.chemotherapy.com ...

Source: www.medicalnewstoday.com --- 26 days ago
Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that 52.3 percent of newly diagnosed bipolar disorder patients are prescribed Antidepressant drugs first line. ...

Source: www.medicalnewstoday.com --- 40 days ago
Women with depression may be much more likely than men to get relief from a commonly used, inexpensive Antidepressant drug, a new national study finds. But many members of both sexes may find that it helps ease their depression symptoms. The persistence of a gender difference in response to the drug - even after the researchers accounted for many complicating factors - suggests that there's a real biological difference in the way the medication affects women compared with men. ...

Source: www.medicalnewstoday.com --- 29 days ago
UroToday.com - Treatment emergent sexual dysfunction is a frequent adverse effect occurring with medication use and is a major influence for premature treatment discontinuation, which leads to treatment failure and costly disease management outcomes. ...

Source: www.medicalnewstoday.com --- 40 days ago
GPs prescribe lower volumes of antidepressants in areas with more Black or South Asian people, suggesting possible disparities in the provision of care. ...