chemotherapy

Research identifies a way to make cancer cells more responsive to chemotherapy

Fri, 24 May 2013 01:13:13 GMT

Source: www.sciencedaily.com --- Thursday, May 23, 2013
Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research explains why some cancer cells don't respond to chemotherapy, and identifies a mechanism to rectify that. ...

Protein preps cells to survive stress of cancer growth and chemotherapy: http://...

Thu, 23 May 2013 18:48:30 GMT

Source: www.facebook.com --- Thursday, May 23, 2013
Protein preps cells to survive stress of cancer growth and chemotherapy: http://medx.cc/288529037 Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors. (Image: Salk Institute for Biological Studies) ...

Protein Preps Cells to Survive Stress of Cancer Growth and Chemotherapy

Thu, 23 May 2013 17:02:39 GMT

Source: www.newswise.com --- Thursday, May 23, 2013
Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors. ...

Program brings alive artistic side of cancer patients getting chemotherapy

Thu, 23 May 2013 15:50:00 GMT

Source: www.macon.com --- Thursday, May 23, 2013
Vincent Van Gogh once said the only time he felt truly alive was when he was painting. ...

Lactate Dehydrogenase B: A Metabolic Marker of Response to Neoadjuvant Chemotherapy in Breast Cancer

Wed, 22 May 2013 13:13:09 GMT

Source: clincancerres.aacrjournals.org --- Wednesday, May 22, 2013
Purpose: Although breast cancers are known to be molecularly heterogeneous, their metabolic phenotype is less well understood and may predict response to chemotherapy. This study aimed to evaluate metabolic genes as individual predictive biomarkers in breast cancer. Methods: mRNA microarray data from breast cancer cell lines were used to identify bimodal genes - those with highest potential for robust high/low classification in clinical assays. Metabolic function was evaluated in vitro for the highest scoring metabolic gene, lactate dehydrogenase B (LDHB). Its expression was associated with neoadjuvant chemotherapy response and relapse within clinical and PAM50-derived subtypes. Results: LDHB was highly expressed in cell lines with glycolytic, basal-like phenotypes. Stable knockdown of LDHB in cell lines reduced glycolytic dependence, linking LDHB expression directly to metabolic function. Using patient datasets, LDHB was highly expressed in basal-like cancers and could predict basal-like subtype within clinical groups (odds ratio = 21 for hormone-receptor (HR)-positive/HER2-negative; odds ratio = 10 for triple-negative). Furthermore, high LDHB predicted pathological complete response (pCR) to neoadjuvant chemotherapy for both HR-positive/HER2-negative (odds ratio = 4.1, P < .001) and triple-negative (odds ratio = 3.0, P = .003) cancers. For triple-negative tumors without pCR, high LDHB post-treatment also identified proliferative ...

Iain Banks posts a new letter to his fans, updating them on his chemotherapy pla...

Wed, 22 May 2013 01:16:42 GMT

Source: www.facebook.com --- Tuesday, May 21, 2013
Iain Banks posts a new letter to his fans, updating them on his chemotherapy plans & writing fan letters to other authors... http://www.guardian.co.uk/books/2013/may/21/iain-banks-updates-fans-cancer Iain Banks posts new update to fans on his cancer www.guardian.co.uk Author discusses possibility of chemotherapy, as well as fan letters he's been sending to other writers ...

Dr. David Spigel: How Do I Discuss the Side Effects of Targeted Therapies, as Compared with Chemotherapy?

Mon, 20 May 2013 13:00:27 GMT

Source: cancergrace.org --- Monday, May 20, 2013
Dr. David Spigel, Sarah Cannon Cancer Center, discusses his perspective on side effects of targeted therapies as compared with standard chemotherapy for patients with lung cancer. Related Posts: Dr. Phil Bonomi, How Do I Discuss the Side Effects of… Dr. Ravi Salgia: How Do I Discuss the Side Effects of… Dr. David Spigel: What are the most promising targeted… Dr. David Spigel: How Do You Discuss the Pros and Cons of… Dr. David Spigel: We’ve Probably Made Maintenance… ...

Early Chemotherapy Impairs Learning in Adolescent Mice

Fri, 17 May 2013 16:30:40 GMT

Source: clincancerres.aacrjournals.org --- Friday, May 17, 2013
Purpose: Among children diagnosed with acute lymphoblastic leukemia (ALL) and given chemotherapy-only treatment, 40% to 70% of survivors experience neurocognitive impairment. The present study used a preclinical mouse model to investigate the effects of early exposure to common ALL chemotherapeutics methotrexate (MTX) and cytarabine (Ara-C) on learning and memory. Experimental Design: Preweanling mouse pups were treated on postnatal day (PND) 14, 15, and 16 with saline, MTX, Ara-C, or a combination of MTX and Ara-C. Nineteen days after treatment (PND 35), behavioral tasks measuring different aspects of learning and memory were administered. Results: Significant impairment in acquisition and retention over both short (1 hour) and long (24 hours) intervals, as measured by autoshaping and novel object recognition tasks, was found following treatment with MTX and Ara-C. Similarly, a novel conditional discrimination task revealed impairment in acquisition for chemotherapy-treated mice. No significant group differences were found following the extensive training component of this task, with impairment following the rapid training component occurring only for the highest MTX and Ara-C combination group. Conclusions: Findings are consistent with those from clinical studies suggesting that childhood cancer survivors are slower at learning new information and primarily exhibit deficits in memory years after successful completion of chemothe ...

Battle Chemotherapy-caused Weight Loss with This

Fri, 17 May 2013 08:49:16 GMT

Source: www.nowpublic.com --- Friday, May 17, 2013
http://www.doctorshealthpress.com/cancer-articles/battle-chemotherapy-caused-weight-loss-with-this Battle chemotherapy-caused Weight Loss with This For many, many people, chemotherapy is a necessary evil. It is what they and their doctors decide is the best chance for... read more ...

Brain Training Helps Clear Cognitive Fog Caused by Chemotherapy

Fri, 17 May 2013 04:00:00 GMT

Source: www.technologyreview.com --- Thursday, May 16, 2013
The mental fuzziness induced by cancer treatment could be eased by cognitive exercises performed online, say researchers. Long-term cancer survivors who use a brain-training program for 12 weeks are more cognitively flexible, verbally fluent and are faster thinkers than survivors who did not train, report investigators. ...

Brain Training May Help Clear Cognitive Fog Caused by Chemotherapy

Fri, 17 May 2013 04:00:00 GMT

Source: www.technologyreview.com --- Thursday, May 16, 2013
The mental fuzziness induced by cancer treatment could be eased by cognitive exercises performed online, say researchers. Cancer survivors sometimes suffer from a condition known as “chemo fog”—a cognitive impairment caused by repeated chemotherapy. A study hints at a controversial idea: that brain-training software might help lift this cognitive cloud. ...

Chemotherapy Education Class - Friday

Thu, 16 May 2013 21:21:53 GMT

Source: www.dukehealth.org --- Thursday, May 16, 2013
For more information, call 919-681-0691 or 919-613-6275 ...

(Refeed) NOVA Short | Chemotherapy and Breast Cancer

Thu, 16 May 2013 17:00:00 GMT

Source: www.pbs.org --- Thursday, May 16, 2013
It used to be standard practice that all patients received chemotherapy after surgery to prevent the recurrence of breast cancer. Today, a genetic test called Oncotype DX allows doctors to analyze the genome of a patient's cancer cells. The results can help oncologists determine whether a patient actually needs to endure chemotherapy post-surgery, thereby avoiding needless suffering. NOVA is produced by WGBH in Boston. National corporate funding for NOVA is provided by The Boeing Company. Major funding for NOVA is provided by David H. Koch, the Corporation for Public Broadcasting, and PBS viewers. ...

Perioperative intravesical chemotherapy in non-muscle-invasive bladder cancer: A systematic ...

Wed, 15 May 2013 23:28:20 GMT

Source: www.urotoday.com --- Wednesday, May 15, 2013
The role for a single dose of intravesical chemotherapy (IVC) after transurethral resection (TUR) remains unclear in patients with non-muscle-invasive bladder cancer (NMIBC). ...

CHEMOTHERAPY DRUG OVERSIGHT NOW IN PLACE

Wed, 15 May 2013 21:13:46 GMT

Source: www.zoomerradio.ca --- Wednesday, May 15, 2013
At Queen’s Park the Wynne Liberals say they’ve closed a gap in oversight after about 12-hundred people in two provinces received diluted chemotherapy drugs. They say that starting today the government will ensure hospitals will purchase drugs only from accredited, licensed or otherwise approved suppliers. They say the Ontario College of Pharmacists will also be responsible to inspect drug preparation facilities where pharmacists and pharmacy technicians practice. Marchese Hospital Solutions prepared the drug-and-saline mixture that was given to four hospitals here in Ontario and one in New Brunswick. Health Canada and the Ontario government have acknowledged that there was no oversight of the company. Health Canada has also taken steps to close the oversight gap in the wake of the drug scare. Some people being treated for cancer were receiving the diluted drugs for as long as a year. ...

Chemotherapy oversight gap narrows in Ontario

Wed, 15 May 2013 19:26:48 GMT

Source: www.cbc.ca --- Wednesday, May 15, 2013
Ontario's governing Liberals say they've closed a gap in oversight after about 1,200 patients in two provinces received diluted chemotherapy drugs. ...

Chemotherapy is a Fraud | Tumors grow faster after chemo!

Tue, 14 May 2013 16:14:20 GMT

Source: truth11.com --- Tuesday, May 14, 2013
...

Chemotherapy Education Class

Mon, 13 May 2013 00:22:09 GMT

Source: www.dukehealth.org --- Sunday, May 12, 2013
Learn about chemotherapy and taking care of yourself during your cancer treatment. ...

New Market Research Report: Chemotherapy Effects - Pipeline Review, H1 2013

Sun, 12 May 2013 16:33:16 GMT

Source: www.sbwire.com --- Sunday, May 12, 2013
Global Markets Direct's, 'chemotherapy Effects - Pipeline Review, H1 2013', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for chemotherapy Effects, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for chemotherapy Effects. chemotherapy Effects - Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. ...