Related Articles WITHDRAWN: Interventions for early stage Hodgkin's disease in children. Cochrane Database Syst Rev. 2008;(4):CD002035 Authors: Louw GG, Pinkerton CR BACKGROUND: Hodgkin's disease is one of the most curable cancers in children, particularly at the early stages. However it is not clear which combinations of treatment strategies are most effective at maintaining high cure rates and minimising long term harmful effects or sequelae of treatment. OBJECTIVES: To assess the effects of radiotherapy, chemotherapy or combined radiotherapy and chemotherapy on relapse free survival and overall survival rates in children with early (stage I to IIA) Hodgkin's disease. SEARCH STRATEGY: We searched the Cochrane Library (issue 4, 2001), MEDLINE (1966 to July 2001), EMBASE, Cinahl, Cancer-CD and reference lists of relevant articles. We also handsearched six journals. SELECTION CRITERIA: Randomised controlled trials of involved field radiotherapy, extended field radiotherapy, anthracycline based chemotherapy regimens, or alkylating chemotherapy agents in children to 19 years of age with Hodgkin's disease. DATA COLLECTION AND ANALYSIS: Trial eligibility and quality were assessed and study authors were contacted for additional information. MAIN RESULTS: Four trials involving 334 children were included. It was not possible to combine the outcomes as they covered different treatment regimens. The trials were of variable quality. One trial co ...
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