Utility values for hypoglycaemia elicited from diabetic and non-diabetic respondents in Canada and the United Kingdom. Health Qual Life Outcomes. 2008 Sep 29;6(1):73 Authors: Levy AR, Christensen TL, Johnson JA ABSTRACT: OBJECTIVE: To elicit societal and patient utilities associated with diabetic symptomatic non-severe hypoglycaemia for three health states: 1) rare (quarterly), 2) intermittent (monthly), 3) and frequent (weekly) hypoglycaemia episodes. METHODS: Using validated health states, time trade-off (TTO) utilities were elicited from 51 Canadian respondents with diabetes and 79 respondents in Canada and 75 respondents in the UK without diabetes. RESULTS AND DISCUSSION: Each hypoglycaemic episode was associated with a reduction in utility and persons with diabetes consistently reported slightly higher utility values than respondents without diabetes. The utility for diabetes without hypoglycaemia ranged from 0.88 to 0.97, the mean utility for rare hypoglycaemic events (quarterly) ranged between 0.85 and 0.94. The utility for the intermittent state (monthly) ranged from 0.77 to 0.90 and from 0.66 to 0.0.83 for the frequent state (weekly). Differences were observed between respondents without diabetes in Canada and the UK. Using a multivariate linear OLS regression, the estimated utilities associated with a single hypoglycaemic event were -0.0033 and -0.0032 for respondents with diabetes and without diabetes, respectively. CONCLUSI ...