Related Articles Echocardiographic and electrocardiographic trends in children with acute Kawasaki disease. Can J Cardiol. 2008 Oct;24(10):776-80 Authors: Crystal MA, Syan SK, Yeung RS, Dipchand AI, McCrindle BW BACKGROUND: Kawasaki disease (KD), while primarily an acute, self-limited, multisystem vasculitis, is more appropriately described as a pancarditis, from a cardiac perspective. Many patients are noted to have ventricular dilation on initial echocardiography; however, functional and structural measurements may remain within the normal range. OBJECTIVE: The authors sought to determine echocardiographic and electrocardiographic trends after acute KD. METHODS: Clinical data were reviewed on all patients presenting with acute KD to the Hospital for Sick Children (Toronto, Ontario). Patients with at least three electrocardiograms and echocardiograms over the first year post-KD were eligible. Mixed linear regression analysis for repeated measures was used to determine trends over time and associated factors. RESULTS: One hundred seventy-six eligible patients were reviewed. Mean initial coronary artery diameter Z-scores were increased, with 4% having aneurysms. The mean (+/- SD) initial Z-score of ejection fraction was 0.40+/-0.84 (P<0.001 versus normal) and left ventricular end-diastolic dimension (LVED) was 0.97+/-0.98 (P<0.001 versus normal). The initial mean QT dispersion was 54+/-23 ms (P<0.001 versus normal). Mixed linear regre ...
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