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Friday, July 04, 2008 --- 47 days ago http://feeds.injuryboard.com/~r/IBnationalnews/~3/326767433/brain-chemical-serot
LEARN MORE EMBL Press Release Injuryboard on SIDS overview Injuryboard News stories on SIDS Injuryboard on Inteview with Dr. Daniel Rubens on research U.S. National Institute of Child Health and Human Development IMAGE SOURCE: Wikimedia Commons/ sleeping baby/ author: Paul Goyette The cause of SIDS or Sudden Infant Death Syndrome has been a mystery, but an imbalance in a brain chemical may hold the key. The chemical in the brain is the neurotransmitter, serotonin. It helps messages pass between brain cells and is most associated with mood, breathing and unconscious functions. In this study, mice were genetically engineered to have slow serotonin production. At first they were normal. "But then they suffered sporadic and unpredictable drops in heart rate and body temperature. More than half of the mice eventually died of these crises during a restricted period of early life. It was at that point that we thought it might have something to do with SIDS," Cornelius Gross of the European Molecular Biology Lab in Italy told Reuters . Interestingly, the mice with no serotonin levels did not die, incidating that malfunctioning serotonin might be worse than none at all. The studies, by the European Molecular Biology Laboratory in Italy, are published in the journal Science. The research equates serotonin to a home thermostat. "When the heat rises past a set point, the heating is shut off. Serotonin has the same type of feedback," Cornelius Gros ... |
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